Interactor 1: MAX (P61244)
Protein max (Class D basic helix-loop-helix protein 4) (bHLHd4) (Myc-associated factor X)
Gene: MAX

Interactor 2: MNT (Q99583)
Max-binding protein MNT (Class D basic helix-loop-helix protein 3) (bHLHd3) (Myc antagonist MNT) (Protein ROX)
Gene: MNT

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.969

The method score is based on:

Property Details
Experiments 9184233, 18271930, 25609649, 29028833, 27705803, 33961781, 20946988
Identification Methods pull down, affinity chromatography technology, two hybrid, tandem affinity purification, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains HLH~HLH
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
and 3 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 160
Hs

1 582
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Gg
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm

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Last updated: 15 Jul 2024