Interactor 1: MAX (P61244)
Protein max (Class D basic helix-loop-helix protein 4) (bHLHd4) (Myc-associated factor X)
Gene: MAX

Interactor 2: MAD3 (Q9BW11)
Max dimerization protein 3 (Max dimerizer 3) (Class C basic helix-loop-helix protein 13) (bHLHc13) (Max-associated protein 3) (Max-interacting transcriptional repressor MAD3) (Myx)
Gene: MXD3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.972

The method score is based on:

Property Details
Experiments 28514442, 10593926, 33961781, 29028833, 27705803, 9528857, 9184233, 10229200, 10918583
Identification Methods affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains HLH~HLH
Common GO terms GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0046983 - protein dimerization activity
and 1 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 160
Hs

1 206
+ Hs
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+ Rn
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+ Gg
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+ Hs

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Last updated: 15 Jul 2024