HitPredict

Interactor 1: MAX (P61244)
Protein max (Class D basic helix-loop-helix protein 4) (bHLHd4) (Myc-associated factor X)
Gene: MAX

Interactor 2: SP130 (Q9H0E3)
Histone deacetylase complex subunit SAP130 (130 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p130)
Gene: SAP130

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	25609649, 33961781
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 160 Hs			1 1048
+	Hs
		347854 MYC_HUMAN (14-105): 1.81e-21: 91.5: 34.74		SP130_HUMAN (1-1048): 2.19e-131: 426: 100.00
+	Hs
		1314318 MAD3_HUMAN (13-142): 5.16e-18: 78.8: 21.21		SP130_HUMAN (1-1048): 2.19e-131: 426: 100.00
+	Hs
		347505 MYC_HUMAN (14-105): 1.81e-21: 91.5: 34.74		PRG4_HUMAN (142-936): 1.82e-30: 132: 11.36
+	Hs
		346789 MYC_HUMAN (14-105): 1.81e-21: 91.5: 34.74		MDC1_HUMAN (11-926): 1.17e-29: 130: 9.43
+	Hs
		347122 MYC_HUMAN (14-105): 1.81e-21: 91.5: 34.74		SRCAP_HUMAN (17-830): 2.84e-24: 112: 10.93
+	Hs
		1079724 USF2_HUMAN (16-115): 1.18e-24: 99.1: 29.91		CIC_HUMAN (284-939): 3.09e-10: 67: 10.76
+	Hs
		607835 USF1_HUMAN (10-115): 4.62e-23: 94.1: 30.97		CIC_HUMAN (284-939): 3.09e-10: 67: 10.76
+	Hs
		546008 MYOD1_HUMAN (11-151): 1.24e-24: 98.4: 16.33		KMT2C_HUMAN (364-832): 7.84e-09: 62.5: 15.83
+	Hs
		347455 MYC_HUMAN (14-105): 1.81e-21: 91.5: 34.74		TITIN_HUMAN (59-898): 8.03e-10: 65.5: 9.13
+	Hs
		379663 MYCN_HUMAN (7-101): 2.1e-21: 91.1: 33.67		TITIN_HUMAN (59-898): 8.03e-10: 65.5: 9.13
+	Hs
		346499 MYC_HUMAN (14-105): 1.81e-21: 91.5: 34.74		MAP1A_HUMAN (7-679): 5.66e-09: 62.8: 8.31