HitPredict

Interactor 1: MAX (P61244)
Protein max (Class D basic helix-loop-helix protein 4) (bHLHd4) (Myc-associated factor X)
Gene: MAX

Interactor 2: ING3 (Q9NXR8)
Inhibitor of growth protein 3 (p47ING3)
Gene: ING3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29028833, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 160 Hs			1 418
+	Hs
		348059 MYC_HUMAN (14-105): 1.81e-21: 91.5: 34.74		ING3_HUMAN (1-418): 1.64e-142: 414: 100.00
+	Hs
		519737 MYCL_HUMAN (7-104): 3.77e-20: 86.9: 30.77		ING3_HUMAN (1-418): 1.64e-142: 414: 100.00
+	Hs
		347756 MYC_HUMAN (14-105): 1.81e-21: 91.5: 34.74		DIDO1_HUMAN (110-410): 3.65e-40: 155: 14.74
+	Hs
		379799 MYCN_HUMAN (7-101): 2.1e-21: 91.1: 33.67		DIDO1_HUMAN (110-410): 3.65e-40: 155: 14.74
+	Hs
		1079732 USF2_HUMAN (16-115): 1.18e-24: 99.1: 29.91		ING1_HUMAN (33-162): 1.96e-30: 123: 16.30
+	Hs
		1314319 MAD3_HUMAN (13-142): 5.16e-18: 78.8: 21.21		ING2_HUMAN (229-417): 8.84e-35: 132: 27.75
+	Hs
		545983 MYOD1_HUMAN (11-151): 1.24e-24: 98.4: 16.33		TAF3_HUMAN (324-407): 1.09e-17: 87.4: 24.72
+	Hs
		348105 MYC_HUMAN (14-105): 1.81e-21: 91.5: 34.74		CXXC1_HUMAN (340-418): 1.04e-17: 87.4: 28.24