Interactor 1: RL26 (P61254)
Large ribosomal subunit protein uL24 (60S ribosomal protein L26)
Gene: RPL26

Interactor 2: MDM2 (Q00987)
E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27) (Double minute 2 protein) (Hdm2) (Oncoprotein Mdm2) (RING-type E3 ubiquitin transferase Mdm2) (p53-binding protein Mdm2)
Gene: MDM2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 0.55 0.675

The method score is based on:

Property Details
Experiments 18951086, 20542919, 23169665, 21988832
Identification Methods affinity chromatography technology, enzymatic study, two hybrid, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006977 - DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
and 1 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024