HitPredict

Interactor 1: MGN (P61326)
Protein mago nashi homolog
Gene: MAGOH

Interactor 2: SRSF1 (Q07955)
Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit)
Gene: SRSF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	23084401
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Mago_nashi~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck and 1 others more... GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 146 Hs			1 248
+	Hs
		899477 MGN_HUMAN (1-146): 5.83e-92: 264: 100.00		SRSF9_HUMAN (1-239): 2.72e-66: 206: 60.25
+	Hs
		899478 MGN_HUMAN (1-146): 5.83e-92: 264: 100.00		SRSF5_HUMAN (14-183): 8.03e-61: 194: 41.48
+	Hs
		899479 MGN_HUMAN (1-146): 5.83e-92: 264: 100.00		SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51
+	Hs
		899469 MGN_HUMAN (1-146): 5.83e-92: 264: 100.00		SRSF4_HUMAN (17-243): 1.36e-49: 171: 37.66
+	Hs
		899458 MGN_HUMAN (1-146): 5.83e-92: 264: 100.00		SRSF3_HUMAN (15-99): 9.33e-28: 105: 43.53
+	Hs
		952069 MGN2_HUMAN (1-146): 1.32e-91: 263: 98.63		SRSF3_HUMAN (15-99): 9.33e-28: 105: 43.53
+	Hs
		899499 MGN_HUMAN (1-146): 5.83e-92: 264: 100.00		SRSF7_HUMAN (14-105): 7.34e-23: 94.8: 40.22