HitPredict

Interactor 1: D6R9G5 (D6R9G5)
Kelch like family member 2
Gene: KLHL2

Interactor 2: ACTZ (P61163)
Alpha-centractin (Centractin) (ARP1) (Actin-RPV) (Centrosome-associated actin homolog)
Gene: ACTR1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 144 Hs			1 376
+	Hs
		307162 KLHL2_HUMAN (1-144): 7.79e-44: 153: 70.83		ACTZ_HUMAN (1-376): 0: 771: 100.00
+	Hs
		89956 D6R9G5_HUMAN (1-144): 1.71e-57: 177: 100.00		ACTY_HUMAN (1-376): 0: 728: 90.43
+	Hs
		307157 KLHL2_HUMAN (1-144): 7.79e-44: 153: 70.83		ACTY_HUMAN (1-376): 0: 728: 90.43
+	Hs
		307166 KLHL2_HUMAN (1-144): 7.79e-44: 153: 70.83		ACTC_HUMAN (5-376): 0: 576: 52.93
+	Dm
		361180 KELC_DROME (46-144): 2.3e-25: 102: 32.32		ACT4_DROME (11-376): 0: 612: 52.70
+	Hs
		915528 KLHL3_HUMAN (8-144): 2.96e-28: 110: 43.80		ACTA_HUMAN (5-376): 0: 576: 52.66
+	Hs
		152484 ENC1_HUMAN (53-141): 4.83e-26: 104: 28.89		ACTB_HUMAN (7-376): 0: 580: 52.41
+	Rn
		892235 KLH17_RAT (58-143): 6.05e-26: 103: 36.17		ACTB_RAT (7-376): 0: 580: 52.41
+	Mm
		929797 KLH17_MOUSE (58-143): 6.05e-26: 103: 36.17		ACTG_MOUSE (7-376): 0: 580: 52.67
+	Hs
		933075 KLH20_HUMAN (39-143): 3.74e-27: 107: 30.70		ACTS_HUMAN (5-376): 0: 576: 52.39
+	Mm
		659359 IPP_MOUSE (66-144): 2.34e-24: 99.1: 31.77		ACTS_MOUSE (5-376): 0: 576: 52.39
+	Hs
		891883 KLHL7_HUMAN (87-143): 6.35e-21: 89.4: 42.11		ACTB_HUMAN (7-376): 0: 580: 52.41