HitPredict

Interactor 1: D6R9G5 (D6R9G5)
Kelch like family member 2
Gene: KLHL2

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	BTB~Cullin
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 144 Hs			1 768
+	Hs
		307170 KLHL2_HUMAN (1-144): 7.79e-44: 153: 70.83		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Mm
		1225041 KLHL2_MOUSE (1-144): 2.31e-43: 151: 68.06		CUL3_MOUSE (1-768): 0: 949: 99.48
+	Hs
		1042489 KLHL4_HUMAN (5-143): 1.05e-28: 111: 21.02		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041718 KLH26_HUMAN (58-144): 2.61e-28: 110: 31.82		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042768 KLHL3_HUMAN (8-144): 2.96e-28: 110: 43.80		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042026 Q8N4I8_HUMAN (8-144): 1.22e-28: 107: 43.80		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042881 KLH20_HUMAN (39-143): 3.74e-27: 107: 30.70		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041852 KLH17_HUMAN (21-143): 2.06e-26: 105: 27.48		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042727 KLH13_HUMAN (39-143): 3.91e-26: 104: 28.07		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		152489 ENC1_HUMAN (53-141): 4.83e-26: 104: 28.89		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Rn
		78189 KLH17_RAT (58-143): 6.05e-26: 103: 36.17		CUL3_RAT (1-768): 0: 951: 99.61
+	Hs
		1042167 KLHL6_HUMAN (33-144): 1.3e-25: 102: 26.96		CUL3_HUMAN (1-768): 0: 951: 100.00
+	At
		1226186 BPM1_ARATH (16-144): 1.74e-30: 114: 14.62		CUL3A_ARATH (9-768): 0: 842: 51.45
+	At
		1341268 BPM2_ARATH (16-144): 7.01e-27: 105: 14.62		CUL3A_ARATH (9-768): 0: 842: 51.45
+	At
		1226178 BPM1_ARATH (16-144): 1.74e-30: 114: 14.62		CUL3B_ARATH (9-768): 0: 826: 50.92
+	Hs
		1043281 KLHL3_HUMAN (8-144): 2.96e-28: 110: 43.80		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1041189 KLHL4_HUMAN (5-143): 1.05e-28: 111: 21.02		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Rn
		70072 KLH17_RAT (58-143): 6.05e-26: 103: 36.17		B1WBY1_RAT (17-768): 0: 709: 30.53
+	Hs
		1041237 KLH13_HUMAN (39-143): 3.91e-26: 104: 28.07		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		152488 ENC1_HUMAN (53-141): 4.83e-26: 104: 28.89		CUL1_HUMAN (18-768): 0: 707: 30.57