HitPredict

Interactor 1: D6R9G5 (D6R9G5)
Kelch like family member 2
Gene: KLHL2

Interactor 2: KEAP1 (Q14145)
Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (INrf2) (Kelch-like protein 19)
Gene: KEAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	BACK~BTB, BTB~BTB
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 144 Hs			1 624
+	Hs
		307172 KLHL2_HUMAN (1-144): 7.79e-44: 153: 70.83		KEAP1_HUMAN (1-624): 0: 584: 100.00
+	Hs
		89972 D6R9G5_HUMAN (1-144): 1.71e-57: 177: 100.00		KLH17_HUMAN (26-610): 1.5e-163: 484: 36.32
+	Hs
		307225 KLHL2_HUMAN (1-144): 7.79e-44: 153: 70.83		KLH13_HUMAN (3-609): 6.31e-164: 485: 25.48
+	Hs
		307188 KLHL2_HUMAN (1-144): 7.79e-44: 153: 70.83		KLH17_HUMAN (26-610): 1.5e-163: 484: 36.32
+	Hs
		1121501 KLH26_HUMAN (58-144): 2.61e-28: 110: 31.82		KLHL9_HUMAN (34-609): 8.46e-159: 471: 26.61
+	Hs
		1121499 KLH26_HUMAN (58-144): 2.61e-28: 110: 31.82		KLH28_HUMAN (59-609): 1.16e-154: 458: 34.76
+	Hs
		1121471 KLH26_HUMAN (58-144): 2.61e-28: 110: 31.82		KLH24_HUMAN (20-624): 2.57e-152: 453: 27.92
+	Hs
		89993 D6R9G5_HUMAN (1-144): 1.71e-57: 177: 100.00		KLHL3_HUMAN (466-624): 3.66e-38: 151: 34.16
+	Hs
		307227 KLHL2_HUMAN (1-144): 7.79e-44: 153: 70.83		KLHL3_HUMAN (466-624): 3.66e-38: 151: 34.16
+	Hs
		307154 KLHL2_HUMAN (1-144): 7.79e-44: 153: 70.83		KLHL2_HUMAN (470-624): 2.88e-33: 136: 33.12
+	Hs
		1299555 KLHL4_HUMAN (5-143): 1.05e-28: 111: 21.02		KLHL5_HUMAN (470-624): 2.33e-44: 171: 38.71
+	Hs
		1319382 KLHL4_HUMAN (5-143): 1.05e-28: 111: 21.02		KLHL1_HUMAN (470-624): 5.2e-43: 166: 38.07
+	Hs
		89968 D6R9G5_HUMAN (1-144): 1.71e-57: 177: 100.00		KLH12_HUMAN (498-623): 1.05e-20: 98.3: 26.92
+	Hs
		307182 KLHL2_HUMAN (1-144): 7.79e-44: 153: 70.83		KLH12_HUMAN (498-623): 1.05e-20: 98.3: 26.92
+	Hs
		307183 KLHL2_HUMAN (1-144): 7.79e-44: 153: 70.83		KLH26_HUMAN (402-618): 4.06e-20: 96.4: 21.40
+	Hs
		1120765 KLH26_HUMAN (58-144): 2.61e-28: 110: 31.82		KLH12_HUMAN (498-623): 1.05e-20: 98.3: 26.92
+	Hs
		1121468 KLH26_HUMAN (58-144): 2.61e-28: 110: 31.82		KLH26_HUMAN (402-618): 4.06e-20: 96.4: 21.40
+	Hs
		1121494 KLH26_HUMAN (58-144): 2.61e-28: 110: 31.82		KLH25_HUMAN (516-623): 1.33e-14: 79.1: 19.27
+	Hs
		152492 KLH26_HUMAN (58-144): 2.61e-28: 110: 31.82		ENC1_HUMAN (516-621): 2.83e-13: 74.8: 17.76