HitPredict

Interactor 1: D6R9G5 (D6R9G5)
Kelch like family member 2
Gene: KLHL2

Interactor 2: KLH12 (Q53G59)
Kelch-like protein 12 (CUL3-interacting protein 1) (DKIR homolog) (hDKIR)
Gene: KLHL12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	BACK~BTB, BTB~BTB
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 144 Hs			1 568
+	Hs
		307182 KLHL2_HUMAN (1-144): 7.79e-44: 153: 70.83		KLH12_HUMAN (1-568): 2.43e-180: 522: 100.00
+	Hs
		89972 D6R9G5_HUMAN (1-144): 1.71e-57: 177: 100.00		KLH17_HUMAN (11-566): 1.87e-162: 479: 40.40
+	Hs
		89962 D6R9G5_HUMAN (1-144): 1.71e-57: 177: 100.00		KEAP1_HUMAN (8-564): 2.73e-161: 475: 35.88
+	Hs
		1120765 KLH26_HUMAN (58-144): 2.61e-28: 110: 31.82		KLH12_HUMAN (1-568): 2.43e-180: 522: 100.00
+	Hs
		307188 KLHL2_HUMAN (1-144): 7.79e-44: 153: 70.83		KLH17_HUMAN (11-566): 1.87e-162: 479: 40.40
+	Hs
		307172 KLHL2_HUMAN (1-144): 7.79e-44: 153: 70.83		KEAP1_HUMAN (8-564): 2.73e-161: 475: 35.88
+	Hs
		307154 KLHL2_HUMAN (1-144): 7.79e-44: 153: 70.83		KLHL2_HUMAN (13-567): 3.8e-158: 466: 41.36
+	Hs
		1121499 KLH26_HUMAN (58-144): 2.61e-28: 110: 31.82		KLH28_HUMAN (15-565): 1.89e-155: 458: 37.77
+	Hs
		1299555 KLHL4_HUMAN (5-143): 1.05e-28: 111: 21.02		KLHL5_HUMAN (360-567): 3.93e-59: 211: 36.54
+	Hs
		1319382 KLHL4_HUMAN (5-143): 1.05e-28: 111: 21.02		KLHL1_HUMAN (365-567): 7.55e-59: 210: 37.93
+	Hs
		307225 KLHL2_HUMAN (1-144): 7.79e-44: 153: 70.83		KLH13_HUMAN (380-568): 2.64e-43: 165: 28.06
+	Hs
		89993 D6R9G5_HUMAN (1-144): 1.71e-57: 177: 100.00		KLHL3_HUMAN (422-568): 1.81e-34: 139: 36.05
+	Hs
		307227 KLHL2_HUMAN (1-144): 7.79e-44: 153: 70.83		KLHL3_HUMAN (422-568): 1.81e-34: 139: 36.05
+	Hs
		307183 KLHL2_HUMAN (1-144): 7.79e-44: 153: 70.83		KLH26_HUMAN (365-568): 5.54e-30: 126: 23.26
+	Hs
		1121501 KLH26_HUMAN (58-144): 2.61e-28: 110: 31.82		KLHL9_HUMAN (380-568): 3.91e-43: 164: 27.55
+	Hs
		152492 KLH26_HUMAN (58-144): 2.61e-28: 110: 31.82		ENC1_HUMAN (378-568): 9.99e-32: 131: 21.29
+	Hs
		1121468 KLH26_HUMAN (58-144): 2.61e-28: 110: 31.82		KLH26_HUMAN (365-568): 5.54e-30: 126: 23.26
+	Hs
		1121471 KLH26_HUMAN (58-144): 2.61e-28: 110: 31.82		KLH24_HUMAN (394-568): 1.15e-28: 122: 29.67
+	Hs
		1121494 KLH26_HUMAN (58-144): 2.61e-28: 110: 31.82		KLH25_HUMAN (471-567): 4.6e-11: 67.5: 16.33