HitPredict

Interactor 1: D6R9G5 (D6R9G5)
Kelch like family member 2
Gene: KLHL2

Interactor 2: WNK3 (Q9BYP7)
Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase lysine-deficient 3) (Protein kinase with no lysine 3)
Gene: WNK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 144 Hs			1 1800
+	Hs
		307211 KLHL2_HUMAN (1-144): 7.79e-44: 153: 70.83		WNK3_HUMAN (1-1800): 0: 1277: 100.00
+	Hs
		1317206 KLHL3_HUMAN (8-144): 2.96e-28: 110: 43.80		WNK3_HUMAN (1-1800): 0: 1277: 100.00
+	Hs
		307234 KLHL2_HUMAN (1-144): 7.79e-44: 153: 70.83		WNK2_HUMAN (1-719): 2.5e-112: 400: 49.73
+	Hs
		89986 D6R9G5_HUMAN (1-144): 1.71e-57: 177: 100.00		WNK1_HUMAN (27-1637): 1.09e-101: 366: 26.62
+	Hs
		682058 KLHL3_HUMAN (8-144): 2.96e-28: 110: 43.80		AKT1_HUMAN (37-470): 5.05e-133: 425: 17.48
+	Hs
		307216 KLHL2_HUMAN (1-144): 7.79e-44: 153: 70.83		WNK1_HUMAN (27-1637): 1.09e-101: 366: 26.62
+	Hs
		1355222 KLHL3_HUMAN (8-144): 2.96e-28: 110: 43.80		WNK2_HUMAN (1-719): 2.5e-112: 400: 49.73
+	Hs
		1330745 KLHL3_HUMAN (8-144): 2.96e-28: 110: 43.80		WNK1_HUMAN (27-1637): 1.09e-101: 366: 26.62
+	Hs
		307202 KLHL2_HUMAN (1-144): 7.79e-44: 153: 70.83		WNK4_HUMAN (601-866): 1.79e-33: 143: 24.44
+	Hs
		1294943 KLHL3_HUMAN (8-144): 2.96e-28: 110: 43.80		WNK4_HUMAN (601-866): 1.79e-33: 143: 24.44