HitPredict

Interactor 1: D6R9G5 (D6R9G5)
Kelch like family member 2
Gene: KLHL2

Interactor 2: FXL17 (Q9UF56)
F-box/LRR-repeat protein 17 (F-box and leucine-rich repeat protein 17) (F-box only protein 13)
Gene: FBXL17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	BTB~LRR_6
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 144 Hs			1 701
+	Hs
		307226 KLHL2_HUMAN (1-144): 7.79e-44: 153: 70.83		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1121505 KLH26_HUMAN (58-144): 2.61e-28: 110: 31.82		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1354637 KLHL3_HUMAN (8-144): 2.96e-28: 110: 43.80		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1354642 KLH20_HUMAN (39-143): 3.74e-27: 107: 30.70		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1164601 KLH17_HUMAN (21-143): 2.06e-26: 105: 27.48		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1350481 KLH13_HUMAN (39-143): 3.91e-26: 104: 28.07		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		152501 ENC1_HUMAN (53-141): 4.83e-26: 104: 28.89		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1201316 KBTB6_HUMAN (44-144): 2.65e-25: 102: 26.96		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1262088 KBTB7_HUMAN (44-144): 1.18e-25: 102: 28.70		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1327770 KLH25_HUMAN (53-141): 1.31e-25: 102: 27.78		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1120825 KLH12_HUMAN (65-144): 3.22e-24: 98.7: 37.04		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1245066 KBTB8_HUMAN (53-144): 3.45e-24: 98.7: 28.42		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1354646 IPP_HUMAN (66-144): 4.72e-24: 98.3: 29.41		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1164633 KLH24_HUMAN (48-144): 1.04e-23: 97.5: 27.10		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1354639 KLH21_HUMAN (61-142): 1.29e-23: 97.2: 39.76		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1049349 KEAP1_HUMAN (42-143): 1.51e-23: 96.8: 21.74		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1221252 KLHL7_HUMAN (87-143): 6.35e-21: 89.4: 42.11		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1348054 KLH28_HUMAN (95-143): 2.06e-16: 76.5: 48.98		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00