HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: DAB2 (P98082)
Disabled homolog 2 (Adaptor molecule disabled-2) (Differentially expressed in ovarian carcinoma 2) (DOC-2) (Differentially-expressed protein 2)
Gene: DAB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 770
+	Hs
		925189 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		DAB2_HUMAN (1-770): 3.91e-90: 301: 100.00
+	Hs
		545320 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		DAB2_HUMAN (1-770): 3.91e-90: 301: 100.00
+	Hs
		833562 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		NUMB_HUMAN (22-635): 7.43e-47: 179: 14.20
+	Hs
		833571 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		NUMB_HUMAN (22-635): 7.43e-47: 179: 14.20
+	Hs
		436206 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		NUMB_HUMAN (22-635): 7.43e-47: 179: 14.20
+	Hs
		900638 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		ANS1B_HUMAN (12-227): 1.36e-43: 172: 19.01
+	Hs
		833576 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		NUMB_HUMAN (22-635): 7.43e-47: 179: 14.20
+	Hs
		833560 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		NUMB_HUMAN (22-635): 7.43e-47: 179: 14.20
+	Hs
		545266 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		NUMB_HUMAN (22-635): 7.43e-47: 179: 14.20
+	Hs
		833559 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		NUMB_HUMAN (22-635): 7.43e-47: 179: 14.20
+	Mm
		892714 RAC3_MOUSE (1-179): 4.85e-74: 223: 57.54		ANS1B_MOUSE (12-230): 5.35e-41: 164: 18.67
+	Hs
		925491 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		ANS1A_HUMAN (1-227): 5e-36: 148: 19.05
+	Hs
		297820 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		K0754_HUMAN (247-770): 7.02e-32: 136: 10.75
+	Hs
		297823 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		K0754_HUMAN (247-770): 7.02e-32: 136: 10.75
+	Hs
		892522 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		ANS1A_HUMAN (1-227): 5e-36: 148: 19.05
+	Hs
		297809 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		K0754_HUMAN (247-770): 7.02e-32: 136: 10.75
+	Hs
		297827 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		K0754_HUMAN (247-770): 7.02e-32: 136: 10.75
+	Hs
		253547 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		CAPON_HUMAN (19-299): 8.52e-35: 141: 13.91
+	Hs
		297812 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		K0754_HUMAN (247-770): 7.02e-32: 136: 10.75
+	Hs
		297819 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		K0754_HUMAN (247-770): 7.02e-32: 136: 10.75