HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: SNTB2 (Q13425)
Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin-3) (SNT3) (Syntrophin-like) (SNTL)
Gene: SNTB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras, PH~Ras
Common GO terms	GO:0005886 - plasma membrane GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 540
+	Hs
		925250 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		SNTB2_HUMAN (18-540): 1.13e-164: 480: 100.00
+	Hs
		950970 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		SNTB2_HUMAN (18-540): 1.13e-164: 480: 100.00
+	Hs
		893970 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		SNTB2_HUMAN (18-540): 1.13e-164: 480: 100.00
+	Hs
		545355 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		SNTB2_HUMAN (18-540): 1.13e-164: 480: 100.00
+	Hs
		158270 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		LIN7A_HUMAN (82-202): 4.94e-35: 133: 32.23
+	Hs
		951362 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		900424 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		DLG1_HUMAN (2-419): 1.78e-27: 119: 15.51
+	Hs
		925239 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		DLG1_HUMAN (2-419): 1.78e-27: 119: 15.51
+	Mm
		925797 RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22		DLG4_MOUSE (66-394): 4.96e-27: 117: 16.32
+	Hs
		436278 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		DLG1_HUMAN (2-419): 1.78e-27: 119: 15.51
+	Hs
		950954 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		DLG1_HUMAN (2-419): 1.78e-27: 119: 15.51
+	Hs
		893948 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		DLG1_HUMAN (2-419): 1.78e-27: 119: 15.51
+	Hs
		545346 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		DLG1_HUMAN (2-419): 1.78e-27: 119: 15.51
+	Mm
		1111996 Q3TLP8_MOUSE (1-193): 3.88e-75: 226: 51.64		DLG4_MOUSE (66-394): 4.96e-27: 117: 16.32
+	Hs
		900762 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		DLG3_HUMAN (117-399): 4.14e-22: 102: 15.97
+	Hs
		951207 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		DLG3_HUMAN (117-399): 4.14e-22: 102: 15.97
+	Hs
		900820 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		MAGI1_HUMAN (69-261): 1.09e-15: 82.6: 17.96
+	Hs
		900710 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		INADL_HUMAN (7-369): 2.84e-15: 81.5: 12.73
+	Hs
		925536 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		MAGI1_HUMAN (69-261): 1.09e-15: 82.6: 17.96
+	Hs
		894333 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		MAGI1_HUMAN (69-261): 1.09e-15: 82.6: 17.96