HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: EPHA7 (Q15375)
Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)
Gene: EPHA7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~fn3
Common GO terms	GO:0005886 - plasma membrane GO:0050919 - negative chemotaxis GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 998
+	Hs
		925297 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		EPHA7_HUMAN (1-998): 0: 1310: 100.00
+	Hs
		436317 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		EPHA7_HUMAN (1-998): 0: 1310: 100.00
+	Hs
		951011 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		EPHA7_HUMAN (1-998): 0: 1310: 100.00
+	Hs
		872423 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		EPHA5_HUMAN (6-988): 0: 1197: 62.65
+	Hs
		436223 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		EPHA5_HUMAN (6-988): 0: 1197: 62.65
+	Hs
		872424 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		EPHA5_HUMAN (6-988): 0: 1197: 62.65
+	Hs
		665194 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		EPHA2_HUMAN (29-989): 0: 1080: 50.42
+	Hs
		665201 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		EPHA2_HUMAN (29-989): 0: 1080: 50.42
+	Hs
		436169 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		EPHA2_HUMAN (29-989): 0: 1080: 50.42
+	Hs
		665208 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		EPHA2_HUMAN (29-989): 0: 1080: 50.42
+	Hs
		665192 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		EPHA2_HUMAN (29-989): 0: 1080: 50.42
+	Hs
		872518 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		EPHB4_HUMAN (18-989): 0: 1023: 48.58
+	Hs
		872522 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		EPHB4_HUMAN (18-989): 0: 1023: 48.58
+	Hs
		436224 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		EPHB4_HUMAN (18-989): 0: 1023: 48.58
+	Hs
		872525 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		EPHB4_HUMAN (18-989): 0: 1023: 48.58
+	Hs
		412115 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		FYN_HUMAN (627-891): 1.29e-62: 224: 43.45
+	Hs
		412123 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		FYN_HUMAN (627-891): 1.29e-62: 224: 43.45
+	Hs
		789109 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		FRK_HUMAN (611-886): 1.46e-62: 223: 41.01
+	Hs
		411948 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		FYN_HUMAN (627-891): 1.29e-62: 224: 43.45
+	Hs
		412113 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		FYN_HUMAN (627-891): 1.29e-62: 224: 43.45