HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: RHGBA (Q6P4F7)
Rho GTPase-activating protein 11A (Rho-type GTPase-activating protein 11A)
Gene: ARHGAP11A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	32203420
Identification Methods	fluorescent resonance energy transfer
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 1023
+	Hs
		900637 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		SRGP1_HUMAN (5-582): 1.8e-82: 292: 16.75
+	Hs
		70663 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		MYO9A_HUMAN (23-519): 1.21e-80: 291: 17.20
+	Ce
		88245 RAC1_CAEEL (1-193): 2.07e-80: 238: 55.44		D3YT54_CAEEL (36-560): 4.07e-83: 283: 19.35
+	Mm
		1265268 RHOA_MOUSE (1-193): 4.1e-81: 240: 99.48		SRGP1_MOUSE (57-582): 5.69e-75: 270: 16.91
+	Hs
		64681 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG32_HUMAN (3-633): 1.03e-73: 269: 14.92
+	Hs
		49631 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG10_HUMAN (20-451): 6.34e-74: 262: 17.08
+	Hs
		900540 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG29_HUMAN (18-647): 6.28e-72: 262: 17.12
+	Hs
		900634 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG22_HUMAN (41-561): 1.47e-74: 262: 19.25
+	Hs
		901000 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG23_HUMAN (37-433): 1.45e-69: 256: 17.99
+	Hs
		900997 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		GMIP_HUMAN (19-448): 2.38e-70: 255: 17.31
+	Hs
		655297 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		P85A_HUMAN (50-555): 1.39e-70: 251: 15.92
+	Hs
		900532 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHGBB_HUMAN (1-238): 3.02e-74: 247: 87.95
+	Hs
		900443 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		MYO9B_HUMAN (21-404): 4.23e-66: 246: 17.25
+	Hs
		129262 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		P85B_HUMAN (48-555): 1.92e-65: 237: 16.93
+	Hs
		900412 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG01_HUMAN (45-243): 1.01e-58: 210: 30.20
+	Mm
		1125742 RHOA_MOUSE (1-193): 4.1e-81: 240: 99.48		RHG01_MOUSE (45-243): 8.04e-58: 208: 27.72
+	Sc
		419681 RHO1_YEAST (3-188): 1.51e-97: 283: 73.12		LRG1_YEAST (42-246): 4.11e-13: 75.9: 27.73
+	Sp
		195119 RHO1_SCHPO (1-193): 2.83e-94: 274: 66.83		RGA1_SCHPO (64-204): 4.1e-11: 69.3: 32.67
+	Hs
		900817 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG07_HUMAN (46-215): 3.49e-12: 73.2: 32.00
+	Hs
		900429 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG05_HUMAN (47-232): 9.01e-10: 65.1: 29.69