HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: TRAF7 (Q6Q0C0)
E3 ubiquitin-protein ligase TRAF7 (EC 2.3.2.-) (EC 2.3.2.27) (RING finger and WD repeat-containing protein 1) (RING finger protein 119) (RING-type E3 ubiquitin transferase TRAF7) (TNF receptor-associated factor 7)
Gene: TRAF7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34215617
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 670
+	Hs
		925367 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		TRAF7_HUMAN (1-670): 1.55e-180: 530: 100.00
+	Hs
		894143 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		TRAF7_HUMAN (1-670): 1.55e-180: 530: 100.00
+	Hs
		545451 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		TRAF7_HUMAN (1-670): 1.55e-180: 530: 100.00
+	Hs
		951210 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		FBXW7_HUMAN (70-499): 3.77e-45: 173: 12.60
+	Hs
		436191 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		LIS1_HUMAN (140-426): 1.68e-23: 105: 10.82
+	Mm
		892718 CDC42_MOUSE (1-193): 5.51e-77: 230: 52.33		LIS1_MOUSE (140-426): 1.46e-23: 105: 10.82
+	Hs
		900348 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		WDR5_HUMAN (99-424): 5.66e-20: 93.7: 10.21
+	Hs
		436239 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		WDR5_HUMAN (99-424): 5.66e-20: 93.7: 10.21