HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: ZCCHV (Q7Z2W4)
Zinc finger CCCH-type antiviral protein 1 (ADP-ribosyltransferase diphtheria toxin-like 13) (ARTD13) (Inactive Poly [ADP-ribose] polymerase 13) (PARP13) (Zinc finger CCCH domain-containing protein 2) (Zinc finger antiviral protein) (ZAP)
Gene: ZC3HAV1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 902
+	Hs
		925389 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		ZCCHV_HUMAN (1-902): 0: 1277: 100.00
+	Hs
		436373 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		ZCCHV_HUMAN (1-902): 0: 1277: 100.00
+	Hs
		951107 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		ZCCHV_HUMAN (1-902): 0: 1277: 100.00
+	Hs
		545465 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		ZCCHV_HUMAN (1-902): 0: 1277: 100.00
+	Hs
		892452 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		ZCCHV_HUMAN (1-902): 0: 1277: 100.00
+	Hs
		915789 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		ZCCHV_HUMAN (1-902): 0: 1277: 100.00
+	Hs
		120510 RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98		ZCCHV_HUMAN (1-902): 0: 1277: 100.00
+	Hs
		900631 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		PARPT_HUMAN (273-895): 0: 578: 23.82
+	Hs
		951109 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		PARPT_HUMAN (273-895): 0: 578: 23.82
+	Hs
		455287 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		PARP1_HUMAN (359-885): 5.92e-142: 449: 13.20