HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: MAGI1 (Q96QZ7)
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (Atrophin-1-interacting protein 3) (AIP-3) (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Trinucleotide repeat-containing gene 19 protein) (WW domain-containing protein 3) (WWP3)
Gene: MAGI1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005886 - plasma membrane GO:0030054 - cell junction GO:0071944 - cell periphery
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 1491
+	Hs
		925536 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		MAGI1_HUMAN (1-1491): 0: 756: 100.00
+	Hs
		900421 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		PTN13_HUMAN (227-1419): 7.85e-57: 220: 10.78
+	Hs
		925236 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		PTN13_HUMAN (227-1419): 7.85e-57: 220: 10.78
+	Hs
		436277 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		PTN13_HUMAN (227-1419): 7.85e-57: 220: 10.78
+	Mm
		925797 RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22		DLG4_MOUSE (14-110): 4.36e-17: 89.1: 19.61
+	Hs
		900762 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		DLG3_HUMAN (16-556): 6.49e-16: 85.6: 12.05
+	Hs
		900424 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		DLG1_HUMAN (14-110): 1.24e-15: 84.8: 19.61
+	Hs
		925239 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		DLG1_HUMAN (14-110): 1.24e-15: 84.8: 19.61
+	Hs
		125308 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		WWP2_HUMAN (215-434): 9.36e-15: 82: 29.39
+	Hs
		125349 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		WWP2_HUMAN (215-434): 9.36e-15: 82: 29.39
+	Hs
		436278 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		DLG1_HUMAN (14-110): 1.24e-15: 84.8: 19.61
+	Hs
		900726 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		PARD3_HUMAN (362-806): 5.29e-13: 76.6: 16.74
+	Hs
		125100 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		WWP2_HUMAN (215-434): 9.36e-15: 82: 29.39
+	Hs
		900710 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		INADL_HUMAN (14-131): 7.48e-13: 76: 14.75
+	Hs
		925463 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		PARD3_HUMAN (362-806): 5.29e-13: 76.6: 16.74
+	Hs
		436425 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		PARD3_HUMAN (362-806): 5.29e-13: 76.6: 16.74
+	Hs
		436419 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		LNX1_HUMAN (13-376): 2.39e-12: 74.1: 11.92
+	Hs
		900463 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		SCRIB_HUMAN (838-1232): 4.22e-09: 63.5: 23.26
+	Hs
		925273 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		SCRIB_HUMAN (838-1232): 4.22e-09: 63.5: 23.26
+	Hs
		436297 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		SCRIB_HUMAN (838-1232): 4.22e-09: 63.5: 23.26