HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: PANX1 (Q96RD7)
Pannexin-1 (PANX1) [Cleaved into: Caspase-activated pannexin-1 (Caspase-activated PANX1)]
Gene: PANX1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 426
+	Hs
		925537 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		PANX1_HUMAN (1-426): 0: 642: 100.00
+	Hs
		436470 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		PANX1_HUMAN (1-426): 0: 642: 100.00
+	Hs
		951247 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		PANX1_HUMAN (1-426): 0: 642: 100.00
+	Hs
		894334 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		PANX1_HUMAN (1-426): 0: 642: 100.00
+	Hs
		545569 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		PANX1_HUMAN (1-426): 0: 642: 100.00
+	Hs
		892546 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		PANX1_HUMAN (1-426): 0: 642: 100.00
+	Hs
		915907 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		PANX1_HUMAN (1-426): 0: 642: 100.00