HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: PKHG2 (Q9H7P9)
Pleckstrin homology domain-containing family G member 2 (PH domain-containing family G member 2)
Gene: PLEKHG2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	11839748
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PH~Ras, Ras~RhoGEF
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 1386
+	Hs
		901037 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		VAV3_HUMAN (13-734): 8.71e-121: 399: 17.48
+	Hs
		548672 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		VAV_HUMAN (12-734): 5.23e-119: 394: 17.59
+	Hs
		855779 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		VAV2_HUMAN (14-674): 9.64e-114: 381: 18.26
+	Hs
		50573 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		PKHG3_HUMAN (8-896): 4.52e-105: 364: 27.85
+	Hs
		50580 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		PKHG3_HUMAN (8-896): 4.52e-105: 364: 27.85
+	Hs
		900768 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		ARHG2_HUMAN (5-827): 8.44e-102: 350: 14.55
+	Hs
		279851 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		TRIO_HUMAN (2-740): 3.3e-94: 338: 19.15
+	Hs
		166479 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		MCF2L_HUMAN (16-617): 2.15e-92: 326: 21.80
+	Hs
		166482 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		MCF2L_HUMAN (16-617): 2.15e-92: 326: 21.80
+	Hs
		500932 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		MCF2_HUMAN (22-498): 1.8e-92: 322: 20.92
+	Mm
		650205 RHOA_MOUSE (1-193): 4.1e-81: 240: 99.48		RGRF1_MOUSE (15-657): 8.78e-87: 311: 13.91
+	Hs
		900947 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		ARHG4_HUMAN (72-494): 1.62e-90: 310: 23.20
+	Hs
		900718 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		PREX1_HUMAN (40-452): 3.91e-85: 309: 24.12
+	Ce
		975575 RAC1_CAEEL (1-193): 2.07e-80: 238: 55.44		VAV_CAEEL (31-732): 5.82e-87: 308: 14.83
+	Hs
		900616 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		PREX2_HUMAN (81-438): 3.83e-83: 302: 22.65
+	Hs
		900916 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		ECT2_HUMAN (8-497): 1.14e-79: 285: 21.79
+	Gg
		1141019 Q6LC82_CHICK (1-193): 8.86e-80: 237: 57.22		ARHG6_CHICK (106-508): 5.92e-79: 279: 22.97
+	Hs
		900648 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		ARHGP_HUMAN (77-522): 1.13e-79: 276: 25.21
+	Sp
		778936 RHO1_SCHPO (1-193): 2.83e-94: 274: 66.83		SCD1_SCHPO (105-417): 1.02e-19: 97.8: 26.45
+	Sp
		778939 RHO5_SCHPO (4-193): 1.09e-93: 273: 65.31		SCD1_SCHPO (105-417): 1.02e-19: 97.8: 26.45