HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: ANLN (Q9NQW6)
Anillin
Gene: ANLN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	1.00	0.799

Property	Details
Experiments	25959226, 31871319
Identification Methods	pull down, x-ray crystallography, affinity chromatography technology
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	GO:0005829 - cytosol GO:0005938 - cell cortex GO:0030496 - midbody
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 1124
+	Hs
		436528 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		894475 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		916000 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Dm
		816388 RHO1_DROME (1-193): 2.84e-76: 228: 86.53		ANLN_DROME (542-1112): 1.6e-160: 511: 29.84
+	Ce
		104473 G5EBV3_CAEEL (2-193): 1.08e-77: 232: 50.52		ANI1_CAEEL (376-1113): 3.32e-131: 430: 19.24
+	Rn
		901291 RHOA_RAT (1-193): 4.1e-81: 240: 99.48		RTKN_RAT (718-1113): 4.11e-121: 385: 17.31
+	Mm
		1207978 RHOA_MOUSE (1-193): 4.1e-81: 240: 99.48		RTKN_MOUSE (721-1113): 1.3e-118: 379: 17.43
+	Hs
		900848 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RTKN_HUMAN (721-1113): 5.09e-119: 380: 16.71
+	Hs
		925570 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		RTKN_HUMAN (721-1113): 5.09e-119: 380: 16.71
+	Hs
		436482 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		RTKN_HUMAN (721-1113): 5.09e-119: 380: 16.71
+	Hs
		915929 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		RTKN_HUMAN (721-1113): 5.09e-119: 380: 16.71
+	Hs
		436397 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		RTKN2_HUMAN (724-1113): 1.08e-112: 365: 18.23
+	Hs
		915820 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		RTKN2_HUMAN (724-1113): 1.08e-112: 365: 18.23