Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA
Interactor 2: RHG35 (Q9NRY4)
Rho GTPase-activating protein 35 (Glucocorticoid receptor DNA-binding factor 1) (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A)
Gene: ARHGAP35
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.89 | 1.00 | 0.944 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9535855, 32203420, 31623230, 9548756, 15102857, unassigned2213 |
| Identification Methods | pull down, affinity chromatography technology, fluorescent resonance energy transfer, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ras~Ras, Ras~RhoGAP |
| Common GO terms | GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane and 4 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
