HitPredict

Interactor 1: RND3 (P61587)
Rho-related GTP-binding protein RhoE (Protein MemB) (Rho family GTPase 3) (Rho-related GTP-binding protein Rho8) (Rnd3)
Gene: RND3

Interactor 2: Q4LE69 (Q4LE69)
1-phosphatidylinositol 4-kinase (EC 2.7.1.67)
Gene: PIK4CA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PI3_PI4_kinase~Ras
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 244 Hs			1 2121
+	Hs
		852505 RND2_HUMAN (20-244): 3.9e-103: 300: 64.00		Q4LE69_HUMAN (1-2121): 0: 2752: 100.00
+	Hs
		436341 RHOC_HUMAN (22-213): 2.02e-92: 271: 49.48		Q4LE69_HUMAN (1-2121): 0: 2752: 100.00
+	Hs
		915720 RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84		Q4LE69_HUMAN (1-2121): 0: 2752: 100.00
+	Hs
		894084 CDC42_HUMAN (24-208): 1.29e-82: 246: 40.00		Q4LE69_HUMAN (1-2121): 0: 2752: 100.00
+	Hs
		925325 RAC1_HUMAN (24-210): 3.03e-80: 240: 43.32		Q4LE69_HUMAN (1-2121): 0: 2752: 100.00
+	Hs
		545417 RAC2_HUMAN (24-211): 1.42e-76: 231: 39.89		Q4LE69_HUMAN (1-2121): 0: 2752: 100.00
+	Hs
		900539 RHOA_HUMAN (25-207): 1.21e-76: 231: 50.27		Q4LE69_HUMAN (1-2121): 0: 2752: 100.00
+	Hs
		892405 RAC3_HUMAN (24-199): 1.42e-75: 229: 43.75		Q4LE69_HUMAN (1-2121): 0: 2752: 100.00
+	Hs
		951044 RHOG_HUMAN (23-208): 1.85e-74: 226: 42.47		Q4LE69_HUMAN (1-2121): 0: 2752: 100.00
+	Hs
		128827 RND2_HUMAN (20-244): 3.9e-103: 300: 64.00		P3C2A_HUMAN (1411-2120): 1.91e-150: 512: 17.85
+	Hs
		128832 CDC42_HUMAN (24-208): 1.29e-82: 246: 40.00		P3C2A_HUMAN (1411-2120): 1.91e-150: 512: 17.85
+	Hs
		787198 RND3_HUMAN (1-244): 1.15e-81: 246: 100.00		PK3CA_HUMAN (1461-2117): 1.72e-151: 500: 21.77
+	Hs
		128803 RAC2_HUMAN (24-211): 1.42e-76: 231: 39.89		P3C2A_HUMAN (1411-2120): 1.91e-150: 512: 17.85
+	Hs
		128833 RHOA_HUMAN (25-207): 1.21e-76: 231: 50.27		P3C2A_HUMAN (1411-2120): 1.91e-150: 512: 17.85
+	Hs
		787203 RAC1_HUMAN (24-210): 3.03e-80: 240: 43.32		PK3CA_HUMAN (1461-2117): 1.72e-151: 500: 21.77
+	Hs
		787196 RAC3_HUMAN (24-199): 1.42e-75: 229: 43.75		PK3CA_HUMAN (1461-2117): 1.72e-151: 500: 21.77
+	Mm
		925806 RAC1_MOUSE (24-210): 3.03e-80: 240: 43.32		PK3CB_MOUSE (1465-2118): 2.73e-140: 468: 18.62
+	Mm
		951511 RHOG_MOUSE (23-208): 1.85e-74: 226: 42.47		PK3CB_MOUSE (1465-2118): 2.73e-140: 468: 18.62
+	Hs
		120195 RHOD_HUMAN (25-211): 1.61e-54: 176: 41.18		P3C2A_HUMAN (1411-2120): 1.91e-150: 512: 17.85
+	Hs
		900702 RHOA_HUMAN (25-207): 1.21e-76: 231: 50.27		PK3C3_HUMAN (1415-2117): 8.86e-127: 424: 17.26