HitPredict

Interactor 1: RND3 (P61588)
Rho-related GTP-binding protein RhoE (Rho family GTPase 3) (Rnd3)
Gene: RND3

Interactor 2: ROCK1 (P70335)
Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)
Gene: ROCK1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 18946488
Identification Methods x-ray crystallography, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Ras, Ras~Rho_Binding
Common GO terms GO:0000139 - Golgi membrane
GO:0005886 - plasma membrane
GO:0032956 - regulation of actin cytoskeleton organization
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 244
Mm

1 1354
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024