HitPredict

Interactor 1: D6RGI3 (D6RGI3)
Septin
Gene: SEPTIN11

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	32812023
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0015630 - microtubule cytoskeleton GO:0030424 - axon GO:0043197 - dendritic spine
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 425 Hs			1 758
+	Hs
		496998 SEPT6_HUMAN (2-424): 0: 563: 82.31		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497368 SEPT8_HUMAN (2-424): 0: 562: 79.11		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497668 SEP11_HUMAN (1-399): 0: 551: 100.00		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		807 A0A087X142_HUMAN (2-424): 0: 524: 77.00		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497093 SEPT7_HUMAN (7-424): 0: 517: 38.88		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Mm
		498157 SEPT6_MOUSE (2-424): 0: 562: 82.08		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Mm
		498090 SEPT8_MOUSE (2-424): 0: 547: 79.34		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Rn
		582045 SEPT7_RAT (10-424): 0: 519: 39.15		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94268 SEPT7_RAT (10-424): 0: 519: 39.15		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Hs
		198179 SEPT4_HUMAN (21-354): 5.34e-166: 476: 39.49		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497495 SEPT5_HUMAN (20-354): 3.62e-161: 460: 39.71		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497039 SEPT2_HUMAN (5-350): 2.8e-159: 455: 38.87		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497746 SEPT9_HUMAN (6-316): 1.44e-152: 446: 39.50		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497740 SEPT3_HUMAN (8-306): 2.78e-152: 437: 43.32		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		152655 SEPT7_HUMAN (7-424): 0: 517: 38.88		KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55