HitPredict

Interactor 1: S61A1 (P61619)
Protein transport protein Sec61 subunit alpha isoform 1 (Sec61 alpha-1)
Gene: SEC61A1

Interactor 2: NTRK3 (Q16288)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 476 Hs			1 839
+	Hs
		384593 S61A1_HUMAN (1-476): 0: 717: 100.00		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		609236 S61A1_HUMAN (1-476): 0: 717: 100.00		FGFR3_HUMAN (140-838): 3.83e-170: 514: 23.73
+	Hs
		901479 S61A1_HUMAN (1-476): 0: 717: 100.00		DDR2_HUMAN (527-824): 2.05e-70: 250: 43.30
+	Hs
		901459 S61A1_HUMAN (1-476): 0: 717: 100.00		ROR2_HUMAN (522-828): 2.97e-67: 243: 41.56
+	Hs
		411348 S61A1_HUMAN (1-476): 0: 717: 100.00		INSR_HUMAN (513-824): 1.34e-64: 238: 39.43
+	Hs
		435593 S61A1_HUMAN (1-476): 0: 717: 100.00		IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16
+	Rn
		544803 S61A1_RAT (1-476): 0: 717: 100.00		INSR_RAT (513-824): 3.31e-62: 230: 38.80
+	Hs
		901546 S61A1_HUMAN (1-476): 0: 717: 100.00		ALK_HUMAN (513-816): 2.78e-59: 222: 39.03