Interactor 1: STXB1 (P61764)
Syntaxin-binding protein 1 (MUNC18-1) (N-Sec1) (Protein unc-18 homolog 1) (Unc18-1) (Protein unc-18 homolog A) (Unc-18A) (p67)
Gene: STXBP1

Interactor 2: STX1A (Q16623)
Syntaxin-1A (Neuron-specific antigen HPC-1)
Gene: STX1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.963

The method score is based on:

Property Details
Experiments 12963086, 12093152, 38072052, 15563604, 10449403, 7553862, 32512168, 12519779, unassigned1973
Identification Methods affinity chromatography technology, pull down, unspecified method, two hybrid fragment pooling approach
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains SNARE~Sec1, Sec1~Syntaxin
Common GO terms GO:0000149 - SNARE binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006886 - intracellular protein transport
GO:0010807 - regulation of synaptic vesicle priming
and 3 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 594
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024