HitPredict

Interactor 1: H3 (P61830)
Histone H3
Gene: HHT1

Interactor 2: CAC2 (Q04199)
Chromatin assembly factor 1 subunit p60 (CAF-1 60 kDa subunit)
Gene: CAC2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.748

Property	Details
Experiments	21256037, 24573675, 26804921, 28126821, 18662540, 20188666, 21444721, 23034810, 24209620
Identification Methods	tandem affinity purification, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0006325 - chromatin organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Sc			1 468
+	Hs
		934716 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		CAF1B_HUMAN (1-466): 5.47e-82: 265: 31.08
+	Hs
		952307 H33_HUMAN (1-136): 1.25e-61: 187: 90.44		CAF1B_HUMAN (1-466): 5.47e-82: 265: 31.08
+	Hs
		1024551 H31T_HUMAN (1-136): 1.96e-61: 186: 86.03		CAF1B_HUMAN (1-466): 5.47e-82: 265: 31.08
+	Hs
		1024562 H32_HUMAN (1-136): 6.6e-61: 185: 88.97		CAF1B_HUMAN (1-466): 5.47e-82: 265: 31.08
+	Dm
		53056 H3_DROME (1-136): 6.6e-61: 185: 88.97		A1Z898_DROME (1-462): 3.9e-78: 260: 28.78
+	Sc
		730914 CENPA_YEAST (24-134): 7.32e-41: 137: 53.04		CAC2_YEAST (1-468): 2.12e-93: 292: 100.00
+	Hs
		792992 H31T_HUMAN (1-136): 1.96e-61: 186: 86.03		LIS1_HUMAN (251-458): 1.34e-29: 121: 9.14
+	Hs
		935208 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		TBL1R_HUMAN (182-401): 7.51e-25: 109: 12.01
+	Hs
		867850 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		HIRA_HUMAN (6-231): 8.55e-23: 104: 13.16
+	Hs
		245614 H32_HUMAN (1-136): 6.6e-61: 185: 88.97		TBL1X_HUMAN (182-436): 1.13e-23: 106: 14.72
+	Hs
		867853 H33_HUMAN (1-136): 1.25e-61: 187: 90.44		HIRA_HUMAN (6-231): 8.55e-23: 104: 13.16
+	Mm
		952748 H33_MOUSE (1-136): 1.25e-61: 187: 90.44		HIRA_MOUSE (6-231): 1.38e-22: 103: 13.16
+	Hs
		867878 H32_HUMAN (1-136): 6.6e-61: 185: 88.97		HIRA_HUMAN (6-231): 8.55e-23: 104: 13.16
+	Sc
		690852 H3_YEAST (1-136): 1.51e-56: 174: 100.00		HIR1_YEAST (1-363): 5.13e-25: 110: 11.52
+	At
		886471 H33_ARATH (1-136): 4.81e-62: 187: 87.50		HIRA_ARATH (325-463): 1.6e-15: 81.4: 7.23
+	Hs
		903117 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		WDR5_HUMAN (2-99): 4.14e-11: 66: 17.82
+	Hs
		934971 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		DAW1_HUMAN (365-458): 9.06e-11: 65.6: 13.83
+	Hs
		903128 H33_HUMAN (1-136): 1.25e-61: 187: 90.44		WDR5_HUMAN (2-99): 4.14e-11: 66: 17.82
+	Hs
		903260 H31T_HUMAN (1-136): 1.96e-61: 186: 86.03		WDR5_HUMAN (2-99): 4.14e-11: 66: 17.82
+	Hs
		152879 H31T_HUMAN (1-136): 1.96e-61: 186: 86.03		APAF_HUMAN (372-459): 5.15e-10: 64.1: 9.09