HitPredict

Interactor 1: GBG11 (P61952)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
Gene: GNG11

Interactor 2: GBB4 (Q9HAV0)
Guanine nucleotide-binding protein subunit beta-4 (Transducin beta chain 4)
Gene: GNB4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	12782285
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	G-gamma~WD40
Common GO terms	GO:0005834 - heterotrimeric G-protein complex GO:0007186 - G protein-coupled receptor signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 73 Hs			1 340
+	Hs
		921515 GBG1_HUMAN (1-73): 5.67e-24: 86.9: 75.68		GBB2_HUMAN (1-340): 1.05e-110: 327: 90.00
+	Hs
		929139 GBG1_HUMAN (1-73): 5.67e-24: 86.9: 75.68		Q6FHM2_HUMAN (1-340): 1.05e-110: 327: 90.00
+	Hs
		929145 GBG1_HUMAN (1-73): 5.67e-24: 86.9: 75.68		GBB4_HUMAN (1-340): 1.76e-110: 326: 100.00
+	Hs
		229238 GBG7_HUMAN (16-72): 1.88e-22: 83.1: 42.11		GBB2_HUMAN (1-340): 1.05e-110: 327: 90.00
+	Hs
		837687 GBG10_HUMAN (13-72): 1.62e-22: 83.1: 35.00		GBB2_HUMAN (1-340): 1.05e-110: 327: 90.00
+	Hs
		921761 GBG12_HUMAN (16-72): 4.09e-22: 82.3: 45.61		GBB2_HUMAN (1-340): 1.05e-110: 327: 90.00
+	Hs
		229245 GBG7_HUMAN (16-72): 1.88e-22: 83.1: 42.11		GBB4_HUMAN (1-340): 1.76e-110: 326: 100.00
+	Hs
		837704 GBG10_HUMAN (13-72): 1.62e-22: 83.1: 35.00		GBB4_HUMAN (1-340): 1.76e-110: 326: 100.00
+	Bt
		362122 GBG1_BOVIN (1-73): 1.98e-24: 88.1: 75.68		GBB1_BOVIN (1-340): 1.71e-106: 316: 90.88
+	Hs
		902493 GBG11_HUMAN (1-73): 3.72e-24: 87.3: 100.00		GBB1_HUMAN (1-340): 1.71e-106: 316: 90.88
+	Hs
		920931 GBG1_HUMAN (1-73): 5.67e-24: 86.9: 75.68		GBB1_HUMAN (1-340): 1.71e-106: 316: 90.88
+	Hs
		560869 GBG11_HUMAN (1-73): 3.72e-24: 87.3: 100.00		GBB3_HUMAN (1-340): 1.25e-105: 314: 79.71
+	Hs
		560871 GBG1_HUMAN (1-73): 5.67e-24: 86.9: 75.68		GBB3_HUMAN (1-340): 1.25e-105: 314: 79.71
+	Hs
		229237 GBG7_HUMAN (16-72): 1.88e-22: 83.1: 42.11		GBB1_HUMAN (1-340): 1.71e-106: 316: 90.88
+	Hs
		837686 GBG10_HUMAN (13-72): 1.62e-22: 83.1: 35.00		GBB1_HUMAN (1-340): 1.71e-106: 316: 90.88
+	Hs
		921073 GBG12_HUMAN (16-72): 4.09e-22: 82.3: 45.61		GBB1_HUMAN (1-340): 1.71e-106: 316: 90.88
+	Hs
		229235 GBG7_HUMAN (16-72): 1.88e-22: 83.1: 42.11		GBB3_HUMAN (1-340): 1.25e-105: 314: 79.71
+	Hs
		560865 GBG10_HUMAN (13-72): 1.62e-22: 83.1: 35.00		GBB3_HUMAN (1-340): 1.25e-105: 314: 79.71
+	Hs
		560893 GBG12_HUMAN (16-72): 4.09e-22: 82.3: 45.61		GBB3_HUMAN (1-340): 1.25e-105: 314: 79.71
+	Hs
		154646 GBG7_HUMAN (16-72): 1.88e-22: 83.1: 42.11		GNB5_HUMAN (129-340): 9.12e-43: 154: 23.08