HitPredict

Interactor 1: SUMO2 (P61956)
Small ubiquitin-related modifier 2 (SUMO-2) (HSMT3) (SMT3 homolog 2) (SUMO-3) (Sentrin-2) (Ubiquitin-like protein SMT3B) (Smt3B)
Gene: SUMO2

Interactor 2: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.692

Property	Details
Experiments	22578841
Identification Methods	pull down, enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Rad60-SLD~ZZ
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 95 Hs			1 2414
+	Hs
		879108 SUMO3_HUMAN (1-94): 3.76e-41: 132: 96.81		EP300_HUMAN (1-2414): 0: 1113: 100.00
+	Hs
		902767 SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00		BAZ1A_HUMAN (889-1176): 3.58e-51: 202: 21.31
+	Hs
		902810 SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00		TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50
+	Rn
		1137066 SUMO3_RAT (1-94): 2.04e-42: 135: 95.75		Q5TLG7_RAT (445-1175): 1.42e-39: 163: 14.12
+	Hs
		902596 SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00		BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48
+	At
		1227573 Q8LCF9_ARATH (2-91): 5.27e-25: 94.7: 25.28		GTE2_ARATH (1048-1360): 7.15e-43: 169: 16.18
+	Hs
		928102 SUMO1_HUMAN (1-93): 7.76e-35: 116: 45.36		BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48
+	Hs
		902552 SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00		BPTF_HUMAN (2011-2413): 1.11e-14: 82.9: 12.86
+	Hs
		902585 SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00		MDC1_HUMAN (455-1061): 8.69e-13: 76.6: 11.82
+	Hs
		902654 SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00		PB1_HUMAN (1081-1145): 9.68e-11: 69.8: 36.92
+	Hs
		928157 SUMO1_HUMAN (1-93): 7.76e-35: 116: 45.36		CBP_HUMAN (1752-2400): 4.44e-10: 67.9: 13.25