HitPredict

Interactor 1: SUMO2 (P61956)
Small ubiquitin-related modifier 2 (SUMO-2) (HSMT3) (SMT3 homolog 2) (SUMO-3) (Sentrin-2) (Ubiquitin-like protein SMT3B) (Smt3B)
Gene: SUMO2

Interactor 2: CHD3 (Q12873)
Chromodomain-helicase-DNA-binding protein 3 (CHD-3) (EC 3.6.4.12) (ATP-dependent helicase CHD3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc finger helicase) (hZFH)
Gene: CHD3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.709

Property	Details
Experiments	16169070, 32786267, 21900206, 15383276, 24018422
Identification Methods	two hybrid, pull down, unspecified method, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016605 - PML body
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 95 Hs			1 2000
+	Hs
		928081 SUMO1_HUMAN (1-93): 7.76e-35: 116: 45.36		CHD3_HUMAN (1-2000): 0: 1917: 100.00
+	Hs
		902587 SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00		CHD4_HUMAN (132-1922): 0: 1552: 69.84
+	Dm
		332484 O97102_DROME (1-94): 1.24e-37: 123: 68.09		CHDM_DROME (78-1944): 0: 1408: 52.01
+	Hs
		902761 SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00		CHD8_HUMAN (84-1804): 0: 851: 22.96
+	Hs
		879157 SUMO3_HUMAN (1-94): 3.76e-41: 132: 96.81		CHD8_HUMAN (84-1804): 0: 851: 22.96
+	Hs
		928205 SUMO1_HUMAN (1-93): 7.76e-35: 116: 45.36		CHD8_HUMAN (84-1804): 0: 851: 22.96
+	Hs
		1241448 NF2IP_HUMAN (7-86): 8.07e-25: 97.4: 34.57		CHD8_HUMAN (84-1804): 0: 851: 22.96
+	Zm
		12032 A0A1D6G673_MAIZE (1-75): 6.8e-33: 112: 46.67		A0A1D6FIP6_MAIZE (577-1626): 0: 781: 27.40
+	Hs
		658709 NF2IP_HUMAN (7-86): 8.07e-25: 97.4: 34.57		SMCA1_HUMAN (622-1597): 0: 776: 28.08
+	Hs
		151484 SUMO1_HUMAN (1-93): 7.76e-35: 116: 45.36		CHD2_HUMAN (540-1666): 0: 733: 31.02