HitPredict

Interactor 1: SUMO2 (P61956)
Small ubiquitin-related modifier 2 (SUMO-2) (HSMT3) (SMT3 homolog 2) (SUMO-3) (Sentrin-2) (Ubiquitin-like protein SMT3B) (Smt3B)
Gene: SUMO2

Interactor 2: MDC1 (Q14676)
Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1)
Gene: MDC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.602

Property	Details
Experiments	19394292, 32786267
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 95 Hs			1 2089
+	Hs
		902555 SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00		TP53B_HUMAN (166-1970): 5.58e-75: 280: 8.87
+	Hs
		879166 SUMO3_HUMAN (1-94): 3.76e-41: 132: 96.81		NCOR2_HUMAN (149-1902): 1.48e-73: 276: 8.36
+	Hs
		928082 SUMO1_HUMAN (1-93): 7.76e-35: 116: 45.36		TP53B_HUMAN (166-1970): 5.58e-75: 280: 8.87
+	Hs
		928238 SUMO1_HUMAN (1-93): 7.76e-35: 116: 45.36		NCOR2_HUMAN (149-1902): 1.48e-73: 276: 8.36
+	Hs
		801056 SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00		KI67_HUMAN (38-1868): 2.43e-65: 249: 11.53
+	Hs
		801069 SUMO1_HUMAN (1-93): 7.76e-35: 116: 45.36		KI67_HUMAN (38-1868): 2.43e-65: 249: 11.53
+	Hs
		902632 SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00		NIPBL_HUMAN (869-1889): 2.17e-21: 104: 15.13
+	Hs
		902812 SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00		SRRM2_HUMAN (133-1326): 2.15e-19: 98.4: 8.08