HitPredict

Interactor 1: SUMO2 (P61956)
Small ubiquitin-related modifier 2 (SUMO-2) (HSMT3) (SMT3 homolog 2) (SUMO-3) (Sentrin-2) (Ubiquitin-like protein SMT3B) (Smt3B)
Gene: SUMO2

Interactor 2: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.703

Property	Details
Experiments	19394292, 25533185, 25533188, 37059091
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 95 Hs			1 1834
+	Hs
		879134 SUMO3_HUMAN (1-94): 3.76e-41: 132: 96.81		SLX4_HUMAN (1-1834): 0: 1486: 100.00
+	Hs
		928132 SUMO1_HUMAN (1-93): 7.76e-35: 116: 45.36		SLX4_HUMAN (1-1834): 0: 1486: 100.00
+	Hs
		801056 SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00		KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79
+	Hs
		801069 SUMO1_HUMAN (1-93): 7.76e-35: 116: 45.36		KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79
+	Hs
		902585 SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00		MDC1_HUMAN (801-1763): 7.3e-12: 73.2: 9.54
+	Hs
		902642 SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00		SRCAP_HUMAN (1206-1787): 5.26e-09: 64: 11.45
+	Hs
		928157 SUMO1_HUMAN (1-93): 7.76e-35: 116: 45.36		CBP_HUMAN (885-1778): 4.86e-09: 64: 9.57
+	Hs
		1170070 NF2IP_HUMAN (7-86): 8.07e-25: 97.4: 34.57		SRCAP_HUMAN (1206-1787): 5.26e-09: 64: 11.45