HitPredict

Interactor 1: D9PTP8 (D9PTP8)
Sorting nexin/Vps5-like C-terminal domain-containing protein
Gene: snx-6

Interactor 2: Q9GYJ9 (Q9GYJ9)
PX domain-containing protein
Gene: snx-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.691

Property	Details
Experiments	19123269, 21148288, 20133524, 14704431
Identification Methods	two hybrid, affinity chromatography technology, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005768 - endosome GO:0042147 - retrograde transport, endosome to Golgi GO:0045335 - phagocytic vesicle GO:0090389 - phagosome-lysosome fusion involved in apoptotic cell clearance
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 133 Ce			1 472
+	Hs
		240410 SNX32_HUMAN (3-130): 8.58e-61: 193: 53.13		SNX2_HUMAN (5-470): 6.6e-112: 341: 35.10
+	Hs
		240464 SNX5_HUMAN (3-132): 1.3e-60: 193: 47.69		SNX2_HUMAN (5-470): 6.6e-112: 341: 35.10
+	Ce
		90270 D9PTP5_CAEEL (1-133): 2.18e-56: 183: 100.00		Q9GYJ9_CAEEL (1-472): 1.58e-115: 349: 100.00
+	Hs
		240456 SNX6_HUMAN (3-129): 1.78e-59: 190: 54.33		SNX2_HUMAN (5-470): 6.6e-112: 341: 35.10
+	Dm
		1370164 Q9VLQ9_DROME (3-130): 5.65e-60: 192: 53.91		Q9VQQ6_DROME (2-470): 2.39e-106: 325: 31.01
+	Hs
		1040476 SNX32_HUMAN (3-130): 8.58e-61: 193: 53.13		SNX1_HUMAN (21-470): 9.74e-105: 323: 34.00
+	Hs
		1040543 SNX5_HUMAN (3-132): 1.3e-60: 193: 47.69		SNX1_HUMAN (21-470): 9.74e-105: 323: 34.00
+	Hs
		1040533 SNX6_HUMAN (3-129): 1.78e-59: 190: 54.33		SNX1_HUMAN (21-470): 9.74e-105: 323: 34.00
+	Dm
		112640 M9NDI3_DROME (3-130): 2.2e-57: 186: 51.49		X2J8I7_DROME (2-470): 5.35e-104: 319: 31.01
+	Hs
		1139039 SNX32_HUMAN (3-130): 8.58e-61: 193: 53.13		SNX30_HUMAN (12-469): 4.18e-81: 259: 14.75
+	Hs
		1357509 SNX6_HUMAN (3-129): 1.78e-59: 190: 54.33		SNX7_HUMAN (71-472): 3.76e-78: 250: 16.42
+	Hs
		1378139 SNX5_HUMAN (3-132): 1.3e-60: 193: 47.69		SNX5_HUMAN (68-469): 2.13e-71: 233: 17.34
+	Hs
		307919 SNX6_HUMAN (3-129): 1.78e-59: 190: 54.33		SNX4_HUMAN (35-465): 3.61e-70: 231: 17.83
+	Hs
		1204251 SNX32_HUMAN (3-130): 8.58e-61: 193: 53.13		SNX6_HUMAN (59-468): 3.72e-69: 227: 15.62
+	Ce
		90269 D9PTP5_CAEEL (1-133): 2.18e-56: 183: 100.00		D9PTP5_CAEEL (35-469): 5.15e-65: 219: 18.06