HitPredict

Interactor 1: DCAF7 (P61962)
DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog)
Gene: DCAF7

Interactor 2: CSK21 (P68400)
Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)
Gene: CSNK2A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.752

Property	Details
Experiments	28514442, 27705803, 33961781, 25852190, 35271311, 32707033, 36736316
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 342 Hs			1 391
+	Hs
		902968 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		CSK23_HUMAN (1-391): 5.89e-133: 388: 98.47
+	Hs
		625294 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		CDK2_HUMAN (36-330): 5.34e-122: 356: 29.74
+	Hs
		586656 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08
+	Hs
		934199 RBBP7_HUMAN (10-342): 1.27e-68: 222: 14.51		CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00
+	Hs
		934127 RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98		CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00
+	Hs
		1083317 RBBP7_HUMAN (10-342): 1.27e-68: 222: 14.51		CSK23_HUMAN (1-391): 5.89e-133: 388: 98.47
+	Hs
		997819 RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98		CSK23_HUMAN (1-391): 5.89e-133: 388: 98.47
+	At
		1105866 TTG1_ARATH (12-342): 1.11e-70: 225: 51.47		KSG7_ARATH (39-375): 4.65e-118: 349: 27.95
+	Hs
		586779 RBBP7_HUMAN (10-342): 1.27e-68: 222: 14.51		CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08
+	Hs
		586707 RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98		CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08
+	Hs
		903116 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00
+	Hs
		792970 LIS1_HUMAN (3-151): 7.87e-23: 99.9: 14.82		CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00
+	Hs
		586657 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08
+	Hs
		625202 LIS1_HUMAN (3-151): 7.87e-23: 99.9: 14.82		CDK2_HUMAN (36-330): 5.34e-122: 356: 29.74
+	Hs
		835628 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		GSK3B_HUMAN (39-389): 1.2e-112: 337: 29.12