HitPredict

Interactor 1: DCAF7 (P61962)
DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog)
Gene: DCAF7

Interactor 2: AUTS2 (Q8WXX7)
Autism susceptibility gene 2 protein
Gene: AUTS2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.738

Property	Details
Experiments	25519132, 28514442, 27705803, 33961781, 37689310, 35016035
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 342 Hs			1 1259
+	Hs
		903392 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		AUTS2_HUMAN (1-1259): 1.57e-142: 466: 100.00
+	Mm
		903071 DCAF7_MOUSE (1-342): 5.45e-87: 267: 100.00		Q6PED7_MOUSE (637-1259): 1.68e-63: 230: 92.01
+	Hs
		903030 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		FBSL_HUMAN (79-931): 1.69e-39: 162: 35.03
+	Hs
		903025 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		FBRS_HUMAN (563-885): 1.05e-30: 129: 41.54
+	Hs
		903001 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		CIC_HUMAN (124-1255): 2.4e-10: 67.4: 9.34
+	Hs
		1083355 RBBP7_HUMAN (10-342): 1.27e-68: 222: 14.51		CIC_HUMAN (124-1255): 2.4e-10: 67.4: 9.34
+	Hs
		997865 RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98		CIC_HUMAN (124-1255): 2.4e-10: 67.4: 9.34
+	Hs
		302269 SC31A_HUMAN (23-342): 1.55e-55: 197: 17.56		SC24C_HUMAN (129-416): 2.32e-09: 64.2: 14.10
+	Hs
		1056932 SNR40_HUMAN (116-342): 3.78e-43: 154: 13.66		MDC1_HUMAN (700-1257): 7.36e-10: 65.9: 8.20
+	Hs
		1264784 SNR40_HUMAN (116-342): 3.78e-43: 154: 13.66		TITIN_HUMAN (60-591): 1.15e-09: 65.3: 11.92
+	Hs
		903374 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		KMT2C_HUMAN (430-1258): 3.63e-13: 77: 9.23
+	Hs
		903229 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		NCOA6_HUMAN (63-1250): 4.76e-13: 76.3: 10.27
+	Hs
		903576 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		RERE_HUMAN (10-900): 6.62e-13: 75.9: 9.42
+	Hs
		152622 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		KMT2D_HUMAN (75-890): 1.52e-10: 68.4: 12.98
+	Hs
		903450 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		CIC_HUMAN (124-1255): 2.4e-10: 67.4: 9.34
+	Mm
		903669 WDR5_MOUSE (208-342): 8.98e-29: 115: 11.85		KMT2C_MOUSE (323-1230): 5.99e-10: 66.3: 9.64
+	Hs
		152682 GRWD1_HUMAN (206-342): 9.29e-18: 85.5: 17.61		KMT2D_HUMAN (75-890): 1.52e-10: 68.4: 12.98
+	Hs
		1056974 WDR33_HUMAN (221-341): 6.91e-16: 81: 14.05		MDC1_HUMAN (700-1257): 7.36e-10: 65.9: 8.20
+	Hs
		152663 WDR5B_HUMAN (2-148): 2.99e-13: 71.4: 10.74		KMT2D_HUMAN (75-890): 1.52e-10: 68.4: 12.98
+	Dm
		52421 A1Z7J7_DROME (180-342): 6.15e-10: 62.8: 16.30		X2JDJ3_DROME (22-771): 3.6e-10: 67: 8.97