HitPredict

Interactor 1: DCAF7 (P61962)
DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog)
Gene: DCAF7

Interactor 2: HIPK2 (Q9H2X6)
Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)
Gene: HIPK2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.680

Property	Details
Experiments	27307198, 20940704, 33961781
Identification Methods	affinity chromatography technology, pull down, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0016604 - nuclear body
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 342 Hs			1 1198
+	Hs
		902983 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		DYRK2_HUMAN (160-606): 2.42e-117: 379: 31.04
+	Hs
		625294 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		CDK2_HUMAN (196-470): 1.65e-116: 365: 25.16
+	Sp
		251855 YBE8_SCHPO (8-342): 7.34e-73: 233: 34.73		PPK15_SCHPO (52-610): 3.57e-122: 389: 30.92
+	Hs
		997818 RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98		HIPK4_HUMAN (190-601): 8.3e-117: 378: 42.86
+	Hs
		997923 RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98		DYRK4_HUMAN (173-639): 5.25e-113: 364: 29.33
+	Hs
		793038 LIS1_HUMAN (3-151): 7.87e-23: 99.9: 14.82		TNIK_HUMAN (178-1175): 1.08e-143: 470: 11.35
+	Hs
		903402 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		DYRK2_HUMAN (160-606): 2.42e-117: 379: 31.04
+	Sc
		539289 YP247_YEAST (43-336): 2.17e-20: 94: 13.31		YAK1_YEAST (56-600): 9.8e-117: 383: 30.89
+	Hs
		902911 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		DYR1A_HUMAN (197-530): 6.34e-56: 210: 39.30
+	Hs
		414806 LIS1_HUMAN (3-151): 7.87e-23: 99.9: 14.82		CDK1_HUMAN (196-530): 5.99e-119: 372: 24.27
+	Hs
		903063 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		DYR1B_HUMAN (199-530): 8.9e-55: 204: 36.31
+	Hs
		625202 LIS1_HUMAN (3-151): 7.87e-23: 99.9: 14.82		CDK2_HUMAN (196-470): 1.65e-116: 365: 25.16
+	Dm
		830253 Q9VR53_DROME (2-342): 2.69e-78: 244: 85.67		MNB_DROME (197-530): 1.16e-54: 208: 38.30
+	Hs
		1319415 WDR33_HUMAN (221-341): 6.91e-16: 81: 14.05		DYRK4_HUMAN (173-639): 5.25e-113: 364: 29.33
+	Hs
		997716 RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98		DYR1A_HUMAN (197-530): 6.34e-56: 210: 39.30
+	Hs
		302287 SC31A_HUMAN (23-342): 1.55e-55: 197: 17.56		DYR1A_HUMAN (197-530): 6.34e-56: 210: 39.30
+	Ce
		1259285 Q93759_CAEEL (5-293): 8.74e-25: 106: 12.99		MBK1_CAEEL (205-527): 4.27e-52: 200: 38.79
+	Hs
		1044099 GRWD1_HUMAN (206-342): 9.29e-18: 85.5: 17.61		DYR1A_HUMAN (197-530): 6.34e-56: 210: 39.30