HitPredict

Interactor 1: DCAF7 (P61962)
DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog)
Gene: DCAF7

Interactor 2: FZR1 (Q9UM11)
Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1)
Gene: FZR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33306668
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ANAPC4_WD40~WD40
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 342 Hs			1 496
+	Hs
		1083339 RBBP7_HUMAN (10-342): 1.27e-68: 222: 14.51		FBXW7_HUMAN (87-424): 1.7e-71: 242: 18.68
+	Dm
		1358859 WDS_DROME (208-342): 2.3e-27: 111: 9.63		FBXW7_DROME (20-496): 6.04e-89: 298: 17.46
+	Hs
		903418 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		FBXW7_HUMAN (87-424): 1.7e-71: 242: 18.68
+	Hs
		903171 RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Hs
		997957 RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	Hs
		903551 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		NLE1_HUMAN (52-385): 3.28e-60: 207: 16.32
+	Hs
		302275 SC31A_HUMAN (23-342): 1.55e-55: 197: 17.56		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Hs
		792949 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		LIS1_HUMAN (309-495): 7.12e-53: 185: 19.68
+	Sp
		999842 TUP11_SCHPO (3-253): 3.42e-47: 170: 14.68		TUP12_SCHPO (346-495): 7.82e-30: 125: 20.89
+	Mm
		925836 LIS1_MOUSE (3-151): 6.41e-23: 100: 14.82		LIS1_MOUSE (309-495): 5.38e-53: 185: 19.68
+	Hs
		792935 LIS1_HUMAN (3-151): 7.87e-23: 99.9: 14.82		LIS1_HUMAN (309-495): 7.12e-53: 185: 19.68
+	Hs
		903428 SNR40_HUMAN (116-342): 3.78e-43: 154: 13.66		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Hs
		1288386 SNR40_HUMAN (116-342): 3.78e-43: 154: 13.66		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	Hs
		1240442 POC1A_HUMAN (2-204): 1.46e-29: 118: 18.72		POC1B_HUMAN (31-259): 4.34e-30: 124: 13.19
+	Hs
		903077 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Hs
		903603 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	Dm
		1358845 WDS_DROME (208-342): 2.3e-27: 111: 9.63		WDS_DROME (389-496): 1.28e-24: 106: 17.43
+	Hs
		903349 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		WDR5B_HUMAN (408-495): 1.82e-11: 67.3: 16.15
+	Hs
		903176 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		CDC20_HUMAN (395-494): 7.34e-10: 63: 16.67