HitPredict

Interactor 1: DCAF7 (P61963)
DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog)
Gene: DCAF7

Interactor 2: DDB1 (Q3U1J4)
DNA damage-binding protein 1 (DDB p127 subunit) (Damage-specific DNA-binding protein 1) (UV-damaged DNA-binding factor)
Gene: DDB1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34161765
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CPSF_A~WD40, MMS1_N~WD40
Common GO terms	GO:0005634 - nucleus GO:0016567 - protein ubiquitination GO:0080008 - Cul4-RING E3 ubiquitin ligase complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 342 Mm			1 1140
+	Hs
		902918 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		DDB1_HUMAN (1-1140): 0: 1445: 99.65
+	Hs
		1082202 RBBP7_HUMAN (10-342): 1.27e-68: 222: 14.51		DDB1_HUMAN (1-1140): 0: 1445: 99.65
+	Hs
		997738 RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98		DDB1_HUMAN (1-1140): 0: 1445: 99.65
+	Hs
		1082327 SNR40_HUMAN (116-342): 3.78e-43: 154: 13.66		DDB1_HUMAN (1-1140): 0: 1445: 99.65
+	Hs
		903254 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		DDB1_HUMAN (1-1140): 0: 1445: 99.65
+	Hs
		1082355 GRWD1_HUMAN (206-342): 9.29e-18: 85.5: 17.61		DDB1_HUMAN (1-1140): 0: 1445: 99.65
+	Hs
		1082263 WDR5B_HUMAN (2-148): 2.99e-13: 71.4: 10.74		DDB1_HUMAN (1-1140): 0: 1445: 99.65
+	At
		186944 MSI1_ARATH (17-342): 3.99e-58: 195: 15.00		DDB1A_ARATH (2-1140): 0: 1254: 52.18
+	At
		186951 MSI3_ARATH (8-342): 2.72e-57: 192: 15.86		DDB1A_ARATH (2-1140): 0: 1254: 52.18
+	At
		186950 MSI3_ARATH (8-342): 2.72e-57: 192: 15.86		DDB1B_ARATH (3-1140): 0: 1248: 51.00
+	At
		187019 MSI4_ARATH (48-338): 3.21e-20: 93.3: 19.23		DDB1A_ARATH (2-1140): 0: 1254: 52.18
+	At
		187004 MSI4_ARATH (48-338): 3.21e-20: 93.3: 19.23		DDB1B_ARATH (3-1140): 0: 1248: 51.00
+	Ce
		219829 LIN53_CAEEL (10-342): 2.97e-67: 218: 14.88		O44985_CAEEL (3-1126): 0: 1022: 19.71
+	Hs
		1073168 NLE1_HUMAN (249-341): 1.44e-21: 97.2: 15.05		SF3B3_HUMAN (3-1126): 0: 1097: 21.25
+	Hs
		1073127 GRWD1_HUMAN (206-342): 9.29e-18: 85.5: 17.61		SF3B3_HUMAN (3-1126): 0: 1097: 21.25
+	Ce
		954081 LIN53_CAEEL (10-342): 2.97e-67: 218: 14.88		CPSF1_CAEEL (3-565): 1.55e-111: 382: 21.98
+	Hs
		1014208 NLE1_HUMAN (249-341): 1.44e-21: 97.2: 15.05		CPSF1_HUMAN (4-527): 1.42e-116: 396: 16.01
+	Hs
		1014197 WDR33_HUMAN (221-341): 6.91e-16: 81: 14.05		CPSF1_HUMAN (4-527): 1.42e-116: 396: 16.01