HitPredict

Interactor 1: DCAF7 (P61963)
DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog)
Gene: DCAF7

Interactor 2: RING2 (Q9CQJ4)
E3 ubiquitin-protein ligase RING2 (EC 2.3.2.27) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING-type E3 ubiquitin transferase RING2)
Gene: Rnf2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17296600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0016567 - protein ubiquitination GO:0016604 - nuclear body
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 342 Mm			1 336
+	Hs
		903005 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		RING2_HUMAN (1-336): 2.74e-106: 315: 99.70
+	Mm
		1194979 Q80ZU1_MOUSE (1-342): 2.67e-85: 262: 99.71		RING2_MOUSE (1-336): 2.13e-106: 316: 100.00
+	Mm
		1141971 RBBP7_MOUSE (10-342): 1.03e-68: 222: 14.51		RING2_MOUSE (1-336): 2.13e-106: 316: 100.00
+	Mm
		1141950 RBBP4_MOUSE (10-342): 2.39e-68: 221: 13.98		RING2_MOUSE (1-336): 2.13e-106: 316: 100.00
+	Hs
		997870 RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98		RING2_HUMAN (1-336): 2.74e-106: 315: 99.70
+	Hs
		902886 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		RING1_HUMAN (10-336): 3.44e-66: 215: 51.75
+	Mm
		903677 WDR5_MOUSE (208-342): 8.98e-29: 115: 11.85		RING2_MOUSE (1-336): 2.13e-106: 316: 100.00
+	Hs
		903017 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		PCGF6_HUMAN (30-293): 1.72e-44: 157: 15.36
+	Hs
		902923 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		PCGF3_HUMAN (36-334): 2.56e-43: 151: 17.16
+	Hs
		718385 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		PCGF2_HUMAN (34-332): 3.57e-40: 145: 15.51
+	Hs
		902951 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		PCGF5_HUMAN (34-334): 2.53e-39: 141: 18.24
+	Hs
		749311 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		BRCA1_HUMAN (36-213): 1.88e-33: 132: 25.93
+	Hs
		903014 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		PCGF1_HUMAN (28-336): 1.37e-35: 131: 16.56
+	Hs
		749539 RBBP7_HUMAN (10-342): 1.27e-68: 222: 14.51		BRCA1_HUMAN (36-213): 1.88e-33: 132: 25.93
+	Hs
		749420 RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98		BRCA1_HUMAN (36-213): 1.88e-33: 132: 25.93
+	Hs
		718223 SC31B_HUMAN (23-336): 4.36e-52: 187: 17.38		BMI1_HUMAN (34-332): 2.52e-42: 151: 16.83
+	Hs
		302262 SC31A_HUMAN (23-342): 1.55e-55: 197: 17.56		BRCA1_HUMAN (36-213): 1.88e-33: 132: 25.93
+	Hs
		997828 RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98		RN138_HUMAN (34-190): 2.01e-24: 101: 20.13
+	Dm
		1279331 EBI_DROME (104-342): 5.77e-41: 153: 15.98		Q9VV77_DROME (36-334): 4.84e-45: 155: 18.69
+	Hs
		749764 SNR40_HUMAN (116-342): 3.78e-43: 154: 13.66		BRCA1_HUMAN (36-213): 1.88e-33: 132: 25.93