HitPredict

Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: EIF3I (Q13347)
Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (TGF-beta receptor-interacting protein 1) (TRIP-1) (eIF-3-beta) (eIF3 p36)
Gene: EIF3I

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	33022573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ANAPC4_WD40~WD40
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 334 Hs			1 325
+	Hs
		196984 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		PRP4_HUMAN (95-325): 1.03e-46: 166: 11.67
+	Hs
		903077 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Hs
		903349 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		WDR5B_HUMAN (180-325): 2.45e-34: 129: 13.61
+	Hs
		903428 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93
+	Hs
		792949 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		LIS1_HUMAN (1-82): 2.95e-21: 95.1: 25.61
+	Hs
		1240442 POC1B_HUMAN (5-251): 5.05e-84: 263: 27.89		POC1A_HUMAN (81-324): 1.17e-56: 190: 14.63
+	Hs
		903418 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05
+	Dm
		1358845 WDS_DROME (3-290): 7.53e-92: 279: 31.21		WDS_DROME (177-325): 5.55e-38: 140: 16.67
+	Hs
		209416 PLRG1_HUMAN (2-333): 5.29e-85: 267: 26.05		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Mm
		925836 LIS1_MOUSE (2-289): 1.02e-94: 288: 29.49		LIS1_MOUSE (1-82): 2.73e-21: 95.5: 25.61
+	Hs
		792935 LIS1_HUMAN (2-289): 1.55e-94: 288: 29.49		LIS1_HUMAN (1-82): 2.95e-21: 95.1: 25.61
+	Hs
		209467 PLRG1_HUMAN (2-333): 5.29e-85: 267: 26.05		SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93
+	Hs
		1288273 WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83		SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93
+	Dm
		1358859 WDS_DROME (3-290): 7.53e-92: 279: 31.21		FBXW7_DROME (215-324): 1.96e-15: 79.3: 13.39
+	Sc
		630844 NLE1_YEAST (167-333): 3.95e-41: 152: 23.70		NLE1_YEAST (2-125): 1.27e-34: 133: 21.43
+	Hs
		903551 NLE1_HUMAN (197-332): 1.05e-32: 128: 22.54		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Sp
		999838 TUP11_SCHPO (3-117): 1.07e-31: 126: 25.19		TUP11_SCHPO (171-324): 1.02e-32: 129: 17.39
+	Hs
		1103007 SMU1_HUMAN (30-331): 7.66e-39: 145: 28.71		FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05