HitPredict

Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: H31T (Q16695)
Histone H3.1t (H3/t) (H3t) (H3/g) (Histone H3.4)
Gene: H3-4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	24793694, 21135039, 24788516, 21124902
Identification Methods	affinity chromatography technology, pull down, unspecified method, enzymatic study, x-ray crystallography
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 334 Hs			1 136
+	Hs
		903117 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		903128 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		792992 LIS1_HUMAN (2-289): 1.55e-94: 288: 29.49		H31T_HUMAN (1-136): 2.65e-61: 186: 100.00
+	Hs
		935208 TBL1R_HUMAN (82-333): 6.52e-60: 201: 26.28		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		245614 TBL1X_HUMAN (6-202): 8.72e-54: 187: 26.32		H32_HUMAN (1-136): 1.34e-60: 184: 96.32
+	Hs
		934971 DAW1_HUMAN (144-333): 8.06e-44: 157: 30.69		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		934824 SMU1_HUMAN (30-331): 7.66e-39: 145: 28.71		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Sc
		744561 SWD3_YEAST (29-330): 8.4e-45: 157: 34.47		H3_YEAST (1-136): 1.43e-55: 171: 86.03
+	Hs
		934796 TAF5_HUMAN (163-330): 6.22e-12: 68.6: 25.25		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		1074789 TAF5_HUMAN (163-330): 6.22e-12: 68.6: 25.25		H31T_HUMAN (1-136): 2.65e-61: 186: 100.00
+	Hs
		952358 TAF5_HUMAN (163-330): 6.22e-12: 68.6: 25.25		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		196999 PRP4_HUMAN (244-333): 1.12e-10: 64.2: 19.39		H31_HUMAN (1-136): 6.88e-62: 187: 97.06