HitPredict

Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: WDR36 (Q8NI36)
WD repeat-containing protein 36 (T-cell activation WD repeat-containing protein) (TA-WDRP)
Gene: WDR36

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33022573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ANAPC4_WD40~WD40
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 334 Hs			1 951
+	Hs
		1246488 NLE1_HUMAN (197-332): 1.05e-32: 128: 22.54		WDR36_HUMAN (1-951): 0: 622: 100.00
+	Hs
		903174 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		TBL3_HUMAN (2-361): 3.23e-60: 222: 14.88
+	Hs
		903349 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		WDR5B_HUMAN (50-360): 2.1e-59: 208: 14.82
+	Hs
		725410 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		COPB2_HUMAN (325-850): 2.34e-52: 200: 7.88
+	Hs
		863397 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		COPA_HUMAN (2-263): 7.56e-21: 101: 9.83
+	Hs
		903605 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		PRP19_HUMAN (528-703): 1.05e-20: 98.7: 16.37
+	Hs
		903077 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		WDR5_HUMAN (32-232): 5.32e-20: 94.4: 17.89
+	Hs
		903551 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		NLE1_HUMAN (42-150): 2.8e-12: 72.3: 9.74
+	Hs
		793026 LIS1_HUMAN (2-289): 1.55e-94: 288: 29.49		KTNB1_HUMAN (331-633): 1.83e-28: 124: 16.34
+	Hs
		1240442 POC1B_HUMAN (5-251): 5.05e-84: 263: 27.89		POC1A_HUMAN (123-363): 8.34e-33: 133: 15.39
+	Hs
		792949 LIS1_HUMAN (2-289): 1.55e-94: 288: 29.49		WDR5_HUMAN (32-232): 5.32e-20: 94.4: 17.89
+	Dm
		1358845 WDS_DROME (3-290): 7.53e-92: 279: 31.21		WDS_DROME (613-748): 4.16e-21: 98.2: 18.98
+	Hs
		209498 PLRG1_HUMAN (2-333): 5.29e-85: 267: 26.05		PRP19_HUMAN (528-703): 1.05e-20: 98.7: 16.37
+	Hs
		209416 PLRG1_HUMAN (2-333): 5.29e-85: 267: 26.05		WDR5_HUMAN (32-232): 5.32e-20: 94.4: 17.89
+	Dm
		1180742 Q9VYQ9_DROME (12-333): 2.1e-89: 277: 26.67		Q7KLW9_DROME (560-736): 1.87e-14: 79.1: 17.42
+	Hs
		1310825 WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83		PRP19_HUMAN (528-703): 1.05e-20: 98.7: 16.37
+	Sc
		630844 NLE1_YEAST (167-333): 3.95e-41: 152: 23.70		NLE1_YEAST (29-317): 5.43e-43: 166: 13.08
+	Hs
		1346954 NLE1_HUMAN (197-332): 1.05e-32: 128: 22.54		NLE1_HUMAN (42-150): 2.8e-12: 72.3: 9.74