HitPredict

Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: ARHG2 (Q92974)
Rho guanine nucleotide exchange factor 2 (Guanine nucleotide exchange factor H1) (GEF-H1) (Microtubule-regulated Rho-GEF) (Proliferating cell nucleolar antigen p40)
Gene: ARHGEF2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	27705803, 33472061
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 334 Hs			1 986
+	Hs
		1273271 WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83		ARHG2_HUMAN (1-986): 0: 736: 100.00
+	Hs
		1273255 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		ARHG2_HUMAN (1-986): 0: 736: 100.00
+	Hs
		1231083 POC1B_HUMAN (5-251): 5.05e-84: 263: 27.89		ARG28_HUMAN (11-875): 8.11e-130: 432: 35.80
+	Hs
		1016930 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		AKP13_HUMAN (37-964): 2.77e-144: 478: 35.95
+	Hs
		1137768 POC1B_HUMAN (5-251): 5.05e-84: 263: 27.89		OBSCN_HUMAN (181-949): 2.83e-85: 304: 13.20
+	Hs
		1202775 WDR5B_HUMAN (3-198): 4.87e-59: 194: 30.10		ARHG1_HUMAN (31-698): 5.2e-86: 298: 21.49
+	Hs
		1049720 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		ARHG7_HUMAN (22-779): 1.98e-100: 335: 11.77
+	Hs
		1191352 WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83		ARHG8_HUMAN (128-637): 9.09e-48: 182: 17.75
+	Hs
		1272184 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		ARHG1_HUMAN (31-698): 5.2e-86: 298: 21.49
+	Hs
		1288351 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		ITSN2_HUMAN (222-599): 8.01e-67: 247: 22.90
+	Hs
		61736 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		A6H8W8_HUMAN (222-577): 1.82e-66: 246: 23.45