HitPredict

Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: LSM2 (Q9Y333)
U6 snRNA-associated Sm-like protein LSm2 (Protein G7b) (Small nuclear ribonuclear protein D homolog) (snRNP core Sm-like protein Sm-x5)
Gene: LSM2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33022573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 334 Hs			1 95
+	Hs
		903646 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		LSM4_HUMAN (1-87): 3.25e-32: 110: 32.58
+	Hs
		903091 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		SMD1_HUMAN (1-95): 6.66e-29: 101: 28.42
+	Hs
		903093 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		SMD3_HUMAN (2-88): 6.44e-24: 89.6: 20.69
+	Hs
		903090 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		RUXF_HUMAN (3-71): 2.45e-23: 86.9: 31.43
+	Hs
		209501 PLRG1_HUMAN (2-333): 5.29e-85: 267: 26.05		LSM2_HUMAN (1-95): 4.21e-38: 124: 100.00
+	Hs
		209418 PLRG1_HUMAN (2-333): 5.29e-85: 267: 26.05		RUXF_HUMAN (3-71): 2.45e-23: 86.9: 31.43
+	Hs
		912719 WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83		SMD3_HUMAN (2-88): 6.44e-24: 89.6: 20.69
+	Hs
		911948 WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83		RUXF_HUMAN (3-71): 2.45e-23: 86.9: 31.43
+	Dm
		218374 Q9VPL0_DROME (1-285): 1.56e-79: 247: 23.15		SMD3_DROME (2-74): 2.73e-23: 88.4: 23.29
+	Hs
		1103034 SMU1_HUMAN (30-331): 7.66e-39: 145: 28.71		LSM4_HUMAN (1-87): 3.25e-32: 110: 32.58
+	Hs
		911856 SMU1_HUMAN (30-331): 7.66e-39: 145: 28.71		RUXF_HUMAN (3-71): 2.45e-23: 86.9: 31.43
+	Hs
		912348 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		SMD1_HUMAN (1-95): 6.66e-29: 101: 28.42
+	Hs
		912695 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		SMD3_HUMAN (2-88): 6.44e-24: 89.6: 20.69
+	Hs
		1288404 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		LSM2_HUMAN (1-95): 4.21e-38: 124: 100.00
+	Hs
		1288409 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		LSM4_HUMAN (1-87): 3.25e-32: 110: 32.58
+	Hs
		912352 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		SMD1_HUMAN (1-95): 6.66e-29: 101: 28.42
+	Hs
		912701 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		SMD3_HUMAN (2-88): 6.44e-24: 89.6: 20.69
+	Hs
		911927 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		RUXF_HUMAN (3-71): 2.45e-23: 86.9: 31.43
+	Hs
		196993 PRP4_HUMAN (244-333): 1.12e-10: 64.2: 19.39		SMD3_HUMAN (2-88): 6.44e-24: 89.6: 20.69
+	Hs
		196988 PRP4_HUMAN (244-333): 1.12e-10: 64.2: 19.39		RUXF_HUMAN (3-71): 2.45e-23: 86.9: 31.43