Interactor 1: WDR5 (P61965)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein) (WD repeat-containing protein BIG-3)
Gene: WDR5

Interactor 2: RBBP5 (Q8BX09)
Retinoblastoma-binding protein 5 (RBBP-5)
Gene: RBBP5

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.925

The method score is based on:

Property Details
Experiments 17825402, 26320581, 17500065, 21335234, 21477851, 21448134
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains WD40~WD40
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0035097 - histone methyltransferase complex
GO:0042393 - histone binding
GO:0044666 - MLL3/4 complex
and 3 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 334
Mm

1 538
+ Hs
+ Dr
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024