HitPredict

Interactor 1: LMO4 (P61968)
LIM domain transcription factor LMO4 (Breast tumor autoantigen) (LIM domain only protein 4) (LMO-4)
Gene: LMO4

Interactor 2: SSBP2 (P81877)
Single-stranded DNA-binding protein 2 (Sequence-specific single-stranded-DNA-binding protein 2)
Gene: SSBP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	24981860, 26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 165 Hs			1 361
+	Hs
		946646 LHX8_HUMAN (23-158): 3.95e-48: 160: 39.71		SSBP2_HUMAN (1-361): 6.02e-60: 198: 100.00
+	Mm
		903801 LMO4_MOUSE (1-165): 1.95e-43: 143: 100.00		SSBP2_MOUSE (1-361): 8.29e-60: 198: 99.72
+	Hs
		1148490 LHX8_HUMAN (23-158): 3.95e-48: 160: 39.71		SSBP4_HUMAN (1-361): 2.16e-51: 177: 68.73
+	Hs
		1148491 LHX8_HUMAN (23-158): 3.95e-48: 160: 39.71		SSBP3_HUMAN (5-361): 4.06e-51: 176: 74.16
+	Hs
		899917 ISL1_HUMAN (22-162): 3.73e-39: 137: 36.55		SSBP2_HUMAN (1-361): 6.02e-60: 198: 100.00
+	Mm
		899943 ISL1_MOUSE (22-162): 3.73e-39: 137: 36.55		SSBP2_MOUSE (1-361): 8.29e-60: 198: 99.72
+	Mm
		1207524 LMO3_MOUSE (13-152): 4.29e-41: 136: 47.86		SSBP2_MOUSE (1-361): 8.29e-60: 198: 99.72
+	Hs
		946651 LMO3_HUMAN (13-152): 4.29e-41: 136: 47.86		SSBP2_HUMAN (1-361): 6.02e-60: 198: 100.00
+	Hs
		638493 RBTN1_HUMAN (1-143): 1.92e-36: 125: 48.25		SSBP2_HUMAN (1-361): 6.02e-60: 198: 100.00
+	Hs
		903772 LMO4_HUMAN (1-165): 1.95e-43: 143: 100.00		SSBP4_HUMAN (1-361): 2.16e-51: 177: 68.73
+	Hs
		903773 LMO4_HUMAN (1-165): 1.95e-43: 143: 100.00		SSBP3_HUMAN (5-361): 4.06e-51: 176: 74.16
+	Hs
		899932 ISL1_HUMAN (22-162): 3.73e-39: 137: 36.55		SSBP4_HUMAN (1-361): 2.16e-51: 177: 68.73
+	Hs
		1251453 LMO3_HUMAN (13-152): 4.29e-41: 136: 47.86		SSBP4_HUMAN (1-361): 2.16e-51: 177: 68.73
+	Hs
		899933 ISL1_HUMAN (22-162): 3.73e-39: 137: 36.55		SSBP3_HUMAN (5-361): 4.06e-51: 176: 74.16
+	Mm
		899944 ISL1_MOUSE (22-162): 3.73e-39: 137: 36.55		SSBP3_MOUSE (5-361): 4.06e-51: 176: 74.16
+	Hs
		1251454 LMO3_HUMAN (13-152): 4.29e-41: 136: 47.86		SSBP3_HUMAN (5-361): 4.06e-51: 176: 74.16
+	Hs
		638570 RBTN1_HUMAN (1-143): 1.92e-36: 125: 48.25		SSBP4_HUMAN (1-361): 2.16e-51: 177: 68.73
+	Hs
		297853 LMO4_HUMAN (1-165): 1.95e-43: 143: 100.00		SC24D_HUMAN (85-286): 1.32e-26: 113: 17.73
+	Dm
		284838 O77284_DROME (19-162): 3.92e-36: 128: 47.22		Q9VEB9_DROME (5-333): 1.74e-31: 125: 38.73
+	Ce
		107708 G5EFL5_CAEEL (15-165): 9.96e-35: 130: 18.79		CO4A1_CAEEL (79-356): 6.12e-21: 96.6: 18.79