Interactor 1: LMO4 (P61968)
LIM domain transcription factor LMO4 (Breast tumor autoantigen) (LIM domain only protein 4) (LMO-4)
Gene: LMO4

Interactor 2: SMAD4 (Q13485)
Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (SMAD family member 4) (SMAD 4) (Smad4) (hSMAD4)
Gene: SMAD4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 0.60 0.716

The method score is based on:

Property Details
Experiments 25416956, 32296183, 25502805, 31515488, unassigned1304
Identification Methods two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005667 - transcription regulator complex
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0046872 - metal ion binding
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 165
Hs

1 552
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024