HitPredict

Interactor 1: LMO4 (P61968)
LIM domain transcription factor LMO4 (Breast tumor autoantigen) (LIM domain only protein 4) (LMO-4)
Gene: LMO4

Interactor 2: ASPP2 (Q13625)
Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2)
Gene: TP53BP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.80	0.662

Property	Details
Experiments	25416956
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Ank_2~LIM
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 165 Hs			1 1128
+	Hs
		1043721 LHX4_HUMAN (82-165): 1.58e-12: 65.8: 18.75		ASPP2_HUMAN (1-1128): 0: 599: 100.00
+	Hs
		1251433 LMO3_HUMAN (13-152): 4.29e-41: 136: 47.86		ASPP1_HUMAN (1-1128): 4.45e-135: 439: 45.38
+	Hs
		638561 RBTN1_HUMAN (1-143): 1.92e-36: 125: 48.25		ASPP1_HUMAN (1-1128): 4.45e-135: 439: 45.38
+	Hs
		903734 LMO4_HUMAN (1-165): 1.95e-43: 143: 100.00		KANK2_HUMAN (303-1049): 2.35e-63: 234: 16.00
+	Hs
		1144723 LMO3_HUMAN (13-152): 4.29e-41: 136: 47.86		KANK2_HUMAN (303-1049): 2.35e-63: 234: 16.00
+	Hs
		638513 RBTN1_HUMAN (1-143): 1.92e-36: 125: 48.25		KANK2_HUMAN (303-1049): 2.35e-63: 234: 16.00
+	Hs
		1144790 PDLI7_HUMAN (16-165): 2.61e-33: 123: 20.99		KANK2_HUMAN (303-1049): 2.35e-63: 234: 16.00
+	Hs
		638310 RBTN2_HUMAN (23-140): 7.68e-36: 123: 46.61		KANK2_HUMAN (303-1049): 2.35e-63: 234: 16.00
+	Hs
		823419 PAXI_HUMAN (15-146): 9.22e-30: 115: 21.97		KANK2_HUMAN (303-1049): 2.35e-63: 234: 16.00
+	Hs
		1144801 LHX3_HUMAN (15-78): 1.96e-10: 60.1: 23.08		KANK2_HUMAN (303-1049): 2.35e-63: 234: 16.00
+	Hs
		822638 LHX1_HUMAN (12-77): 4.61e-10: 58.9: 23.88		KANK2_HUMAN (303-1049): 2.35e-63: 234: 16.00
+	Hs
		1219793 LMO3_HUMAN (13-152): 4.29e-41: 136: 47.86		ANKH1_HUMAN (922-1013): 2.42e-20: 100: 30.44
+	Hs
		823450 PAXI_HUMAN (15-146): 9.22e-30: 115: 21.97		ANR52_HUMAN (787-1049): 8.14e-26: 117: 13.86
+	Hs
		823441 PAXI_HUMAN (15-146): 9.22e-30: 115: 21.97		ANKH1_HUMAN (922-1013): 2.42e-20: 100: 30.44
+	Hs
		638375 RBTN2_HUMAN (23-140): 7.68e-36: 123: 46.61		EHMT2_HUMAN (687-995): 4.44e-17: 89.1: 10.35
+	Ce
		105083 G5EFL5_CAEEL (15-165): 9.96e-35: 130: 18.79		G5ECD7_CAEEL (931-1059): 2.42e-13: 76.8: 29.41
+	Hs
		1281166 LHX4_HUMAN (82-165): 1.58e-12: 65.8: 18.75		EHMT2_HUMAN (687-995): 4.44e-17: 89.1: 10.35
+	Hs
		1296429 LHX3_HUMAN (15-78): 1.96e-10: 60.1: 23.08		EHMT2_HUMAN (687-995): 4.44e-17: 89.1: 10.35
+	Hs
		1243832 LHX4_HUMAN (82-165): 1.58e-12: 65.8: 18.75		KMT2C_HUMAN (222-886): 1.84e-09: 64.7: 11.45
+	Hs
		1243849 LHX3_HUMAN (15-78): 1.96e-10: 60.1: 23.08		KMT2C_HUMAN (222-886): 1.84e-09: 64.7: 11.45